Results 61 to 70 of about 57,171 (196)
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng +8 more
wiley +1 more source
The nu-e-bar electron elastic scattering cross-section was measured with a CsI(Tl) scintillating crystal detector array with a total mass of 187 kg at the Kuo-Sheng Nuclear Power Station. The detectors were exposed to a reactor nu-e-bar flux of 6.4 X 10^{
Bilmis, Selcuk +2 more
core +2 more sources
Human Cyclophilins—An Emerging Class of Drug Targets
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Cyclic Adenosine 3',5'-monophosphate (cAMP) is a key second messenger known to directly regulate not only the protein kinase A (PKA) activity but also other important molecules such as the exchange protein activated by cAMP (EPAC), which is as a guanine ...
María Eugenia Mansilla Pareja +4 more
doaj +1 more source
Criterion-related validation (CRV) studies are used to demonstrate the effectiveness of selection procedures. However, traditional CRV studies require significant investment of time and resources, as well as large sample sizes, which often create ...
Allen, Kristin +2 more
doaj +1 more source
Groundwater Temperature Processes and Patterns: Implications for Stream Thermal Regimes
Shallow groundwater temperatures are controlled by ground surface temperatures and are influenced by climate change and land cover changes. Deeper groundwater temperature is constant year‐round, making it cooler (warmer) in the summer (winter) than surface water, and exhibits a lagged response to surface warming.
Barret L. Kurylyk +6 more
wiley +1 more source
“Two birds with one stone” strategy for the lung cancer therapy with bioinspired AIE aggregates
Aggregation-induced emission luminogens (AIEgens) have emerged as novel phototherapeutic agents with high photostability and excellent performance to induce photodynamic and/or photothermal effects.
Yinshan Lin +7 more
doaj +1 more source
ABSTRACT Aim To evaluate the impact of polymorphisms in SOCS‐1, TNF‐α and RANKL on gene expression of RANK, RANKL, TNFRSF1, SOCS‐1, IL‐10, IL‐1β and TNF‐α, and to evaluate the histopathological, immunohistochemical and microbiological aspects of persistent apical periodontitis (PAP) after root canal treatment (RCT) in Brazilian individuals ...
Igor Bassi Ferreira Petean +12 more
wiley +1 more source
Research on WASH sector, environment and water resources in the Central Rift Valley of Ethiopia [PDF]
Peer ReviewedPostprint (published ...
Fantaye, D. +3 more
core
ABSTRACT Background The SYNAPSE phase 3 study demonstrated that mepolizumab significantly improves nasal polyp score (NPS), quality of life and symptom severity in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). Objective We aimed to evaluate mepolizumab effectiveness in a real‐world cohort from 12 tertiary centers in 6 European ...
Isam Alobid +30 more
wiley +1 more source

