Results 91 to 100 of about 13,032 (212)

The gas control module of the cryoablation system (left) connects to a conventional compressed CO2 gas canister used in the carbonated beverage industry and regulates flow to the cryoprobe (right) during cryoablation. [PDF]

open access: yes, 2019
The gas control module of the cryoablation system (left) connects to a conventional compressed CO2 gas canister used in the carbonated beverage industry and regulates flow to the cryoprobe (right) during cryoablation.
Saraswati Sukumar (11083)   +14 more
core   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

open access: yesAdvanced Science, Volume 13, Issue 37, 3 July 2026.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda   +8 more
wiley   +1 more source

Simulation of the Effects of Blood Vessels in a Freezing Tumor

open access: yesZhileng xuebao, 2019
Blood vessels have been studied as an important factor in normal tissue and tumors during cryosurgery. It is of great significance to study the effects of blood vessels during the freezing process.
Song Tao   +4 more
doaj  

Cytomorphology and Molecular Profile of Hyalinizing Clear Cell Carcinoma of the Lung: A Case With Mucinous Differentiation

open access: yesDiagnostic Cytopathology, Volume 54, Issue 7, Page E165-E169, July 2026.
ABSTRACT Hyalinizing clear cell carcinoma (HCCC) of the lung is an exceedingly rare salivary gland‐type neoplasm with limited cytomorphologic description. We report a case highlighting these features. A 3 mm incidental left‐airway lesion enlarged to 7 mm over 5 months, prompting radial endobronchial ultrasound (EBUS)‐guided transbronchial biopsy. Touch
Jeffrey Zijie Lin, Lucy Jager
wiley   +1 more source

End-diastole (a) and end-systole (b) short axis views acquired using the CryoProbe together with a ultra-high spatial resolution of (43×138×300) µm3. [PDF]

open access: yes, 2012
Endo- and epicardial border delineation as well as the depiction of anatomic details of the papillary muscles and trabeculae are improved versus the high resolution CryoProbe images (Figure 3 e,f) due to the enhanced spatial resolution used in the ultra ...
Andreas Pohlmann (148430)   +7 more
core   +1 more source

Feasibility and Safety of Pleuroscopic Cryobiopsy of the Pleura: A Prospective Study

open access: yesCanadian Respiratory Journal, 2018
Background. The aim of this study was thus to evaluate the feasibility and safety of taking biopsy specimens by cryoprobe from the parietal pleura during semirigid pleuroscope. Methods.
Chia-Hung Chen   +6 more
doaj   +1 more source

Sequence‐encoded differences in the conformational ensembles of CITED transcriptional activation domains impact coactivator binding

open access: yesProtein Science, Volume 35, Issue 7, July 2026.
Abstract Recent advances in predicting and modeling conformational ensembles of intrinsically disordered proteins (IDPs) have provided much needed insights into sequence‐ensemble relationships. It is thought that conservation of physicochemical properties, but not the exact identity or order of the amino acids, maintains IDP ensemble properties that ...
To Uyen Do   +4 more
wiley   +1 more source

Phosphoryl Halogen and Hydrogen Bonding Controls the Solid‐State Structures of Aryl Halide‐Containing Phosphonates

open access: yesEuropean Journal of Inorganic Chemistry, Volume 29, Issue 17, 17 June 2026.
Intramolecular (RO)2PO→Halogen interaction versus intermolecular (RO)2PO···HOH hydrogen bonds. Although the O···I distance is shorter than the sum of the van der Waals radii of the atoms involved, there is no covalency involved in this interaction.
David Mross   +6 more
wiley   +1 more source

Development of a Brain‐Penetrant Nurr1 Agonist Tool

open access: yesChemMedChem, Volume 21, Issue 11, 15 June 2026.
Nuclear receptor‐related 1 (Nurr1) is a ligand‐activated transcription factor with neuroprotective properties, thought to hold therapeutic potential in neurodegeneration. Here, we developed a potent, brain‐penetrant Nurr1 agonist to study the effects of pharmacological Nurr1 activation in the CNS in vivo. The ligand‐sensing transcription factor nuclear
Jan Vietor   +7 more
wiley   +1 more source

Total Synthesis and Antimalarial Studies of Caelestines A–C

open access: yesChemMedChem, Volume 21, Issue 11, 15 June 2026.
Total synthesis of caelestines A–C (alkaloids from the Australian ascidian, Aplidium caelestis) was accomplished, constituting the first synthesis of caelestines B and C. Caelestines A–C, with five other novel quinolones, were assessed against Plasmodium falciparum 3D7 and Dd2. Caelestine B was found to be a selective antimalarial alkaloid. Caelestines
Henry S. T. Smith   +3 more
wiley   +1 more source

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