Results 61 to 70 of about 3,957 (196)

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

open access: yesAdvanced Materials, Volume 38, Issue 33, 12 June 2026.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee   +8 more
wiley   +1 more source

Research Progresses in Vitrification by Minimum Volume Method

open access: yesZhileng xuebao, 2018
Vitrification is an effective method in the field of cryopreservation since it can prevent the formation of ice crystals. Vitrification requires ultra-fast cooling rates and high concentrations of cryoprotective agents.
Zhang Xiaomin, Zhou Xinli
doaj  

Synergistic Interaction Between MALAT1/miR‐30b‐5p/BAFF Axis and Inflammatory Cytokines Underlies Rituximab‐Refractory NMOSD

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
The MALAT1/miR‐30b‐5p/BAFF axis is activated in monocytes during NMOSD onset and relapse. The MALAT1/miR‐30b‐5p/BAFF axis is activated in monocytes, thereby facilitating the release of BAFF and inflammatory cytokines (including IL‐1, IL‐6, IL‐8, and TNF‐α).
Meiqun Deng   +8 more
wiley   +1 more source

Mechanistic Insights Into Color and Texture Stability of Frozen Tropical Vegetables: Processing, Modeling, and Preservation Strategies

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
This review elucidates the mechanistic pathways governing color and texture degradation in frozen tropical vegetables, emphasizing pigment oxidation, enzymatic softening, and ice crystal‐induced structural damage. It integrates kinetic, Arrhenius, RSM, and machine‐learning models with advanced preservation strategies to optimize freezing processes ...
Muhammad Muntasir Mahmud   +4 more
wiley   +1 more source

Thermophysical Properties of Cryoprotective Agents IV. Thermal Capacity of Some Cryoprotective Agents, Their Aqueous Solutions and Mixtures

open access: yes, 2011
Систематизированы литературные данные по теплоемкости воды, чистых криопротекторов, их водных растворов и смесей. Построены эмпирические полиномиальные уравнения для расчета теплоемкости воды и чистых криопротекторов в зависимости от температуры.
Попивненко, Л.И.   +2 more
core   +1 more source

Space biomedicine‐oriented bioink and biomimetic blood‒brain barrier

open access: yesVIEW, Volume 7, Issue 3, June 2026.
Bioinks and bioprinting play a pivotal role in the successful delivery of cell models and the fabrication of tissue models for space biomedicine research. This study investigated the effects of hypergravity and vibration on two‐dimensional adherent cells and three‐dimensional embedded cells and provided methods for storing hybrid bioink and high ...
Ranran Yan   +3 more
wiley   +1 more source

Thermophysical Properties of Cryoprotective Agents. V. Thermal Conductivity and Thermal Diffusivity of Some Cryoprotective Agents and Their Aqueous Solutions

open access: yes, 2011
Систематизированы литературные данные по тепло- и температуропроводности воды, чистых криопротекторов и их водных растворов. Построены эмпирические полиномиальные уравнения для расчета тепло- и температуропроводности воды, чистых криопротекторов и их ...
Тимофеева, Е.В.   +2 more
core   +1 more source

Cryo-derived plants through embryogenesis showed same levels of vinblastine and vincristine (anticancer) in Catharanthus roseus and had normal genome size

open access: yesScientific Reports, 2022
Cryopreservation of rare plant materials is an important approach for preserving germplasms and is a good added concept to tissue banking. The preservation of embryogenic cell suspensions is even more valuable as the tissues facilitate in producing ...
A. Mujib   +2 more
doaj   +1 more source

Design, Synthesis, and Evaluation of Coumarin‐Rasagiline Hybrids as Multifunctional Neuroprotective Agents

open access: yesChemMedChem, Volume 21, Issue 10, 27 May 2026.
Novel coumarin‐rasagiline hybrid molecules were designed and synthesized as multifunctional agents targeting key pathological mechanisms of neurodegenerative diseases. These compounds exhibited hMAO‐B inhibitory activity, antioxidant and neuroprotective effects, supported by ADMET profiling and molecular modeling studies. The design of hybrid molecules
Aitor Carneiro   +8 more
wiley   +1 more source

Evaluation of different cryoprotective agents in maintenance of viability of Helicobacter pylori in stock culture media [PDF]

open access: yes, 2010
Four different cryoprotective supplemented stock media were evaluated for maintaining better survival and recovery of H. pylori type strain NCTC 11637 at two different maintenance temperatures of -20 degrees C and -80 degrees C after one month ...
Özlem Yilmaz   +7 more
core   +1 more source

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