Results 61 to 70 of about 1,545,419 (198)

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, Volume 13, Issue 55, 5 October 2026.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Multi‐regional Organoid Biobank Reveals FAK‐ACSL1‐Driven Doxorubicin‐Resistance and Predictive Biomarkers in Breast Cancer

Advanced Science, Volume 13, Issue 55, 5 October 2026.
This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu, Zhijun Qin, Jiapeng Yang, Baoyuan Zhang, Manqing Cao, Peng Wang, Zaiqi Wang, Jinghui Cheng, Lei Wang, Hong Liu, Hui Yang   +10 more
wiley   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, Volume 6, Issue 10, October 2026.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

Advanced NanoBiomed Research, Volume 6, Issue 10, October 2026.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

Deep eutectic solvents as cryoprotective agents for mammalian cells

, 2022
Cryopreservation has facilitated numerous breakthroughs including assisted reproductive technology, stem cell therapies, and species preservation. Successful cryopreservation requires the addition of cryoprotective agents to protect against freezing ...
Nastaran Meftahi (18028699), Gary Bryant (18025564), Andrew Christofferson (18025183), Tamar Greaves (8797919), Aaron Elbourne (18028054), Andrew Martin (8797886), Saffron Bryant (18033136), Miyah Awad (20011098), Calum Drummond (18026164)   +8 more
core  

Viability, Storage Stability, Release Kinetics, and Sensory Attributes of Lactiplantibacillus plantarum ATCC 8014 in Synergistic Cryoprotectant‐Mediated Puree Blend

Applied Research, Volume 5, Issue 5, October 2026.
Synergistic sodium alginate and glycerol protected Lactiplantibacillus plantarum in frozen pumpkin‐carrot purée, maintaining probiotic viability above functional levels for 120 days. The formulation enabled controlled intestinal release, enhanced storage stability, and improved sensory acceptance, supporting its potential as a plant‐based functional ...
Nur Ainaa Nasuha Mustaffa, Siti Fatimah Ibrahim, Noor Azlina Kamaruding, Mohd Al‐Fatihhi Mohd Szali, Shahrulzaman Shaharuddin   +4 more
wiley   +1 more source

Cryo-derived plants through embryogenesis showed same levels of vinblastine and vincristine (anticancer) in Catharanthus roseus and had normal genome size

Scientific Reports, 2022
Cryopreservation of rare plant materials is an important approach for preserving germplasms and is a good added concept to tissue banking. The preservation of embryogenic cell suspensions is even more valuable as the tissues facilitate in producing ...
A. Mujib, Samar Fatima, Moien Qadir Malik   +2 more
doaj   +1 more source

Advances in Agricultural Applications of Lignans

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
This graphical abstract presents lignans as green alternatives to chemical pesticides and antibiotics for agriculture and veterinary use. It illustrates their applications in plant protection (antifungal, insecticidal, herbicidal, fruit preservation) and aquaculture, classifies lignan subtypes from classic to complex forms, highlights limitations like ...
Kaida Li, Huawen Wang, Xiangjie Luo, Feng Hao, Kun Wei, Le Cai   +5 more
wiley   +1 more source

Cryoprotective agents as inducers of erythroleukemic cell differentiation in vitro [PDF]

Blood, 1976
The ability of families of compounds with known and potential cryoprotective properties to induce the differentiation of Friend leukemia cells in vitro was studied. For each agent, both the proportion of differentiated cells in the culture and the total amount of heme/10(7) cells were determined.
H D, Preisler, G, Christoff, E, Taylor
openaire   +3 more sources

INTERACTIONS OF DILUENTS, CRYOPROTECTIVE AGENTS AND STRAW FILLING CAPACITY ON QUALITY AND FERTILIZING ABILITY OF BUFFALO SEMEN [PDF]

Veterinary Medical Journal - Giza, 2003
The present study was carried out on three buffalo bulls. Their semen was extended in three diluents (Milk, Laiciphos and Tris) with three cryoprotec- live agents (Glycerol, DMSO and propylene gly- col.
G SOSA, E EL-DEEB, K EL-SABAGH
doaj   +1 more source