Polyampholytes as Emerging Macromolecular Cryoprotectants [PDF]
Biomacromolecules, 2019 Cellular cryopreservation is a platform technology which underpins cell biology, biochemistry, biomaterials, diagnostics, and the cold chain for emerging cell-based therapies. This technique relies on effective methods for banking and shipping to avoid the need for continuous cell culture.
Christopher Stubbs +3 more
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Osmoprotectants and cryoprotectants for Listeria monocytogenes [PDF]
Letters in Applied Microbiology, 2000 Listeria monocytogenes is a foodborne pathogen that can grow in high osmotic strength environments and at refrigeration temperatures. Glycine betaine, proline betaine, acetylcarnitine, carnitine, gamma-butyrobetaine and 3-dimethylsulphoniopropionate all acted as osmoprotectants, as evidenced by an increase in growth rate of L.
D O, Bayles, B J, Wilkinson
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Aptamer-Facilitated Cryoprotection of Viruses [PDF]
ACS Medicinal Chemistry Letters, 2014 Global vaccination and gene therapy programs have an urgent demand for stabilization of viral vectors at low temperature. We used a quadramer, a bridge-connected DNA tetra-aptamer to antivesicular stomatitis virus (VSV), as a viral cryoprotectant. Results showed that the tetravalent antivirus DNA aptamers protect viral activity during multiple freeze ...
Shahrokh M, Ghobadloo +4 more
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Dissecting the cryoprotection mechanisms for dehydrins [PDF]
Frontiers in Plant Science, 2014 One of the common responses of plants to water deficit is the accumulation of the so-called late embryogenesis abundant (LEA) proteins. In vitro studies suggest that these proteins can protect other macromolecules and cellular structural components from the impairments caused by water limitation.
Cuevas-Velazquez, Cesar L. +2 more
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Genetic suppression of cryoprotectant toxicity
Cryobiology, 2019 We report here a new, unbiased forward genetic method that uses transposon-mediated mutagenesis to enable the identification of mutations that confer cryoprotectant toxicity resistance (CTR). Our method is to select for resistance to the toxic effects of M22, a much-studied whole-organ vitrification solution.
James R, Cypser +4 more
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Cryoprotection without cryoprotectant [PDF]
Acta Crystallographica Section A Foundations and Advances, 2017 Yvonne Thielmann +4 more
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Cryopreservation toxicity and morphological outcomes in <i>Piaractus brachypomus</i> oocytes and embryos. [PDF]
Anim ReprodDigmayer M +9 more
europepmc +1 more source
The effect of cryoprotectant and storage conditions on the aggregation of poly(ethylene glycol)-poly(α-benzyl carboxylate-ε-caprolactone) nanoparticles. [PDF]
J Pharm Pharm SciSarrami N +3 more
europepmc +1 more source
Bis-prodrug cryopreserved lipid nanoparticles with enzymatically triggered release. [PDF]
Nanoscale AdvHogarth C +4 more
europepmc +1 more source
Hydrogel Systems in Plant Germplasm Cryopreservation: A Comprehensive Review. [PDF]
GelsBobrova O +3 more
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