Results 51 to 60 of about 60,128 (260)

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Deciphering Aspergillus section Terrei in Galleria mellonella model: a clade-specific pathogenicity characterization

Microbiology Spectrum
The Aspergillus genus encompasses a diverse array of species, some of which are opportunistic pathogens. Traditionally, human aspergillosis has primarily been linked to a few Aspergillus species, predominantly A. fumigatus.
Roya Vahedi-Shahandashti, Jos Houbraken, Vit Hubka, Martin Meijer, Bettina Gudrun Zelger, Ulrike Binder, Cornelia Lass-Flörl   +6 more
doaj   +1 more source

Delimiting cryptic species within the brown-banded bamboo shark, Chiloscyllium punctatum in the Indo-Australian region with mitochondrial DNA and genome-wide SNP approaches

BMC Ecology and Evolution, 2021
Background Delimiting cryptic species in elasmobranchs is a major challenge in modern taxonomy due the lack of available phenotypic features. Employing stand-alone genetics in splitting a cryptic species may prove problematic for further studies and for ...
Fahmi, Ian R. Tibbetts, Michael B. Bennett, Christine L. Dudgeon   +3 more
doaj   +1 more source

Cryptic species are widespread across vertebrates

Proceedings of the Royal Society B: Biological Sciences
Abstract Many species delimited by morphological data contain two or more species that are distinct based on molecular data (i.e. cryptic species). Cryptic species have important implications for ecology, evolution and conservation. For example, morphology-based species of limited conservation concern can contain cryptic species that ...
Yinpeng Zhang, John J. Wiens
openaire   +2 more sources

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

A practical implementation of large transcriptomic data analysis to resolve cryptic species diversity problems in microbial eukaryotes

BMC Evolutionary Biology, 2018
Background Transcriptome sequencing has become a method of choice for evolutionary studies in microbial eukaryotes due to low cost and minimal sample requirements.
Yonas I. Tekle, Fiona C. Wood
doaj   +1 more source

CRYPTIC SPECIES IN AN INSECTIVOROUS BAT, SCOTOPHILUS DINGANII [PDF]

Journal of Mammalogy, 2006
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Jacobs, David S., Eick, Geeta N., Schoeman, M. Corrie, Matthee, Conrad A.   +3 more
openaire   +1 more source

Protein Disulfide Isomerase Disassembles TDP‐43/G3BP1 Condensates and Antagonizes TDP‐43 Pathological Aggregates

Advanced Science, EarlyView.
Cytoplasmic aggregation of TDP‐43 is a common pathological feature in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer's disease with TDP‐43 pathology. This study reports that wild‐type PDI slows down phase separation of TDP‐43 through direct interaction with TDP‐43.
Jia‐Qi Liu, Hao Liu, Yu‐Xuan Sun, Yuying Li, Xiangyi Liu, Li‐Qiang Wang, Zhaofei Yang, Qi Fu, Xiaojiao Xu, Jie Chen, Yingshuang Zhang, Jun Zhou, Weidong Le, Mengchao Cui, Yi Liang   +14 more
wiley   +1 more source

Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A

Angewandte Chemie, EarlyView.
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham, Edward S. Hems, Daniel C. L. Van, Justin E. Clarke, Sergey Nepogodiev, Julius S. P. Adamson, Christian Bassi, Michael E. Webb, Glyn R. Hemsworth, Orde Q. Munro, Barrie Wilkinson, Ryan F. Seipke   +11 more
wiley   +2 more sources

Diversity and environmental relations of cryptic, systemic Botrytis infections in symptomless hosts.

Frontiers in Plant Science, 2016
Botrytis species are generally considered to be aggressive, necrotrophic plant pathogens. By contrast to this general perception, however, Botrytis species could frequently be isolated from the interior of multiple tissues in apparently healthy hosts of ...
Michael W. Shaw, Christy J. Emmanuel, Christy J. Emmanuel, Deni eEmilda, Deni eEmilda, Razak B. Terhem, Razak B. Terhem, Aminath eShafia, Aminath eShafia, Dimitra eTsamaidi, Dimitra eTsamaidi, Mark eEmblow, Mark eEmblow, Jan A.L. Van Kan   +13 more
doaj   +1 more source