Results 11 to 20 of about 11,020 (173)

Cryptococcal meningitis: A neglected NTD? [PDF]

PLOS Neglected Tropical Diseases, 2017
Although HIV/AIDS has been anything but neglected over the last decade, opportunistic infections (OIs) are increasingly overlooked as large-scale donors shift their focus from acute care to prevention and earlier antiretroviral treatment (ART) initiation.
Molloy, S.F., Chiller, T., Greene, G.S., Burry, J., Govender, N.P., Kanyama, C., Mfinanga, S., Lesikari, S., Mapoure, Y.N., Kouanfack, C., Sini, V., Temfack, E., Boulware, D.R., Dromer, F., Denning, D.W., Day, J., Stone, N.R.H., Bicanic, T., Jarvis, J.N., Lortholary, O., Harrison, T.S., Jaffar, S., Loyse, A.   +22 more
openaire   +7 more sources

Voriconazole as a secondary prophylaxis for cryptococcal meningitis during hematopoietic stem cell transplantation

IDCases, 2021
Antifungal prophylaxis is crucial for successful hematopoietic stem cell transplantation (HSCT). Maintenance therapy with fluconazole (FLCZ) is generally prescribed as secondary prophylaxis in patients with human immunodeficiency virus infection and non ...
Emiko Kashima, Keiki Nagaharu, Kazuko Ino, Yuka Sugimoto, Atsushi Fujieda, Keiki Kawakami, Isao Tawara   +6 more
doaj   +1 more source

Utility of clinical assessment, imaging, and cryptococcal antigen titer to predict AIDS-related complicated forms of cryptococcal meningitis

AIDS Research and Therapy, 2010
Background This study aimed to evaluate the prevalence and predictors of AIDS-related complicated cryptococcal meningitis. The outcome was complicated cryptococcal meningitis: prolonged (≥ 14 days) altered mental status, persistent (≥ 14 days) focal ...
Kandel Sean, Jafari Hamta, Sitapati Amy M, Caperna Joseph, Cachay Edward R, Mathews William C   +5 more
doaj   +1 more source

“False negative” CSF cryptococcal antigen with clinical meningitis: Case reports and review of literature

Medical Mycology Case Reports, 2020
There is an increasing recognition of patients presenting with cryptococcal meningitis despite having a negative CSF cryptococcal antigen (CrAg). In this report, we describe three cases of patients with advanced immunosuppression who presented to ...
Morris K. Rutakingirwa, Tadeo K. Kiiza, Joshua Rhein   +2 more
doaj   +1 more source

Cryptococcal antigenemia is associated with meningitis or death in HIV-infected adults with CD4 100–200 cells/mm3

BMC Infectious Diseases, 2020
Background Cryptococcal antigen (CrAg) screening with fluconazole prophylaxis has been shown to prevent cryptococcal meningitis and mortality for people living with HIV (PLWH) with CD4 
James Wykowski, Sean R. Galagan, Sabina Govere, Carole L. Wallis, Mahomed-Yunus Moosa, Connie Celum, Paul K. Drain   +6 more
doaj   +1 more source

A case report of a brain herniation secondary to cryptococcal meningitis with elevated intracranial pressure in a patient with Human Immunodeficiency Virus/Acquired immunodeficiency syndrome (HIV/AIDS)

IDCases, 2022
Background: Cryptococcal meningitis is a major opportunistic infection in individuals with HIV. The worldwide annual incidence is estimated to be approximately one million cases per year, with the most significant burden in sub-Saharan Africa.
Nehemias Guevara, Abdulrasheed Akande, Mailing Flores Chang, Jane Atallah, Carol Epstein   +4 more
doaj   +1 more source

Another case of cryptococcal meningitis in a person without HIV who injects drugs: A possible risk factor in need of further investigation

Medical Mycology Case Reports, 2022
Cryptococcal meningitis is a fungal central nervous infection typically occurring in patients with severe immunocompromise. We present a case of cryptococcal meningitis occurring in a patient with active injection drug use (IDU) but no immunocompromising
L. Madeline McCrary, Ryan Paulus, J. Kyle Melvin, John Perfect, Becky L. White   +4 more
doaj   +1 more source

Low CD4 count plus coma predicts cryptococcal meningitis in Tanzania

BMC Infectious Diseases, 2007
Background Largely due to the lack of diagnostic reagents, the prevalence and clinical presentation of cryptococcal meningitis in Tanzania is poorly understood. This in turn is limiting the impact of increased fluconazole availability.
Mueller Andreas, Swai Ndealilia S, Mchele John PD, Maro Venance P, Hawkins Alexander T, Kisenge Peter R, Houpt Eric R   +6 more
doaj   +1 more source

Cryptococcal meningitis. [PDF]

Boletin de la Asociacion Medica de Puerto Rico, 1985
Cryptococcosis is a systemic fungal disease and meningitis is the most serious complication. The purpose of this study is to define problems related to its diagnosis and treatment. This is a retrospective analysis of 25 patients admitted from January 1978 to December 1981.
C F, Morales, B, Christenson, J R, Rodríguez, M, Colón, C H, Ramírez-Ronda   +4 more
openaire   +4 more sources

Association of Fcγ receptor IIB polymorphism with cryptococcal meningitis in HIV-uninfected Chinese patients. [PDF]

PLoS ONE, 2012
BACKGROUND: As important regulators of the immune system, the human Fcγ receptors (FcγRs) have been demonstrated to play important roles in the pathogenesis of various infectious diseases.
Xiu-Ping Hu, Ji-Qin Wu, Li-Ping Zhu, Xuan Wang, Bin Xu, Rui-Ying Wang, Xue-Ting Ou, Xin-Hua Weng   +7 more
doaj   +1 more source