Results 51 to 60 of about 13,630 (218)

When to consider an inborn error of immunity: clues for physicians

Internal Medicine Journal, EarlyView.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

Tamoxifen boosted antifungal therapy for cryptococcal meningitis [PDF]

, 2022
Central nervous system infections are of an important focus for clinical research, especially in tropical settings such as Vietnam. Of particular concern is cryptococcal meningitis, a leading cause of death particularly in HIV patients.
Nguyễn Thị Thủy Ngân
core   +1 more source

Performance of cryptococcal antigen lateral flow assay in serum, cerebrospinal fluid, whole blood, and urine in HIV-infected patients with culture-proven cryptococcal meningitis admitted at a Brazilian referral center

Revista do Instituto de Medicina Tropical de São Paulo, 2018
Cryptococcal meningitis is the most common cause of opportunistic meningitis in HIV-infected patients in Brazil and causes unacceptable high mortality rates.
José E. Vidal, Carolina Toniolo, Adriana Paulino, Arnaldo L. Colombo, Marilena dos Anjos Martins, Cristina da Silva Meira, Renata Guise Soares Azevedo, Vera Lucia Pereira-Chioccola, Hélio Rodrigues Gomes, Marcia dos Santos Lazera, Augusto C. Penalva de Oliveira, David R. Boulware   +11 more
doaj   +1 more source

Management of long-term cryptococcal meningitis neoformans in a surviving patient: A case report

Frontiers in Medicine, 2022
Cryptococcal meningitis is a common fungal infection of the central nervous system with high mortality and disability rates. A prominent clinical manifestation is persistent and severe cranial hypertension, which is one of the most critical outcome ...
Shijun Hu, Tao Liu, Shixiong Huang, Hui Liang   +3 more
doaj   +1 more source

Epidemiology and Outcomes of Cryptococcal Infections in Liver Transplant Recipients: A Retrospective Cohort Study at a US Academic Center

Transplant Infectious Disease, EarlyView.
Among 346 liver transplant recipients, rural residence conferred a 3.3‐fold higher risk of cryptococcal infection — a novel finding suggesting environmental exposure or healthcare access barriers may drive susceptibility. Triple immunosuppression and longer waitlist duration were additional risk factors, with very early infection carrying the worst ...
Rachel Sigler, Chloe Hanigan, Atikur Rahman, Isuru Ratnayake, Phani Akella, Lauren Carlini, Chelsea Gorsline, Erica Mackenzie, Albert Eid, Dennis Shoemaker, Ryan Taylor, Stephen Waller   +11 more
wiley   +1 more source

Meningoencephalitis in a Young Immunocompetent Patient

Journal of Investigative Medicine High Impact Case Reports
Cryptococcal meningitis is mainly seen in immunocompromised patients, but in recent years, there has been an increase in cases involving patients with no known immunodeficiencies. These patients have symptomatic presentations that range from indolent and
Michael Ke MD, Neeki Ettefagh, Ahmet Semih Topbas MD, Mehdi Kazemi MD   +3 more
doaj   +1 more source

Molecular diagnosis of cryptococcal meningitis in cerebrospinal fluid: comparison of primer sets for Cryptococcus neoformans and Cryptococcus gattii species complex

Brazilian Journal of Infectious Diseases, 2015
Aim: This study evaluated the use of polymerase chain reaction for cryptococcal meningitis diagnosis in clinical samples. Materials and methods: The sensitivity and specificity of the methodology were evaluated using eight Cryptococcus neoformans/C ...
Marilena dos Anjos Martins, Kate Bastos Santos Brighente, Terezinha Aparecida de Matos, Jose Ernesto Vidal, Daise Damaris Carnietto de Hipólito, Vera Lucia Pereira-Chioccola   +5 more
doaj   +1 more source

Gingival enlargement and dentition loss associated with disseminated Cryptococcus neoformans infection in a dog

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract A 1‐year‐old, female, spayed, mixed‐breed dog was examined by a referring veterinarian for a 1‐week history of sneezing, bilateral mucoid nasal discharge, mild bilateral ocular discharge and stertor. During rhinoscopy, a plant awn foreign body was removed, but upper respiratory signs persisted. Computed tomography of the head revealed findings
Glynn Woods, Allison Volk, Janny Evenhuis, Abbie Metcalfe, Jane E. Sykes   +4 more
wiley   +1 more source

Central Nervous System Vasculitis for Cryptococcosis in an Immunocompetent Patient

Diseases, 2018
Cryptococcal meningitis is a life-threatening condition caused by a fungal pathogen, Cryptococcus neoformans, that can infect both immunosuppressed and immunocompetent hosts. It is an important cause of morbidity and mortality in severely immunodeficient
Dan Zimelewicz Oberman, Liliana Patrucco, Carolina Cuello Oderiz   +2 more
doaj   +1 more source

Cryptococcus meningitis mimicking cerebral septic emboli, a case report series demonstrating injection drug use as a risk factor for development of disseminated disease

BMC Infectious Diseases, 2020
Background Clinicians may be less inclined to consider a diagnosis of cryptococcal meningitis in people without HIV infection or transplant-related immunosuppression. This may lead to a delay in diagnosis particularly if disseminated cryptococcal disease
Christopher Polk, Jacqueline Meredith, Alyssa Kuprenas, Michael Leonard   +3 more
doaj   +1 more source