Results 61 to 70 of about 67,556 (218)

Central Nervous System Vasculitis for Cryptococcosis in an Immunocompetent Patient

Diseases, 2018
Cryptococcal meningitis is a life-threatening condition caused by a fungal pathogen, Cryptococcus neoformans, that can infect both immunosuppressed and immunocompetent hosts. It is an important cause of morbidity and mortality in severely immunodeficient
Dan Zimelewicz Oberman, Liliana Patrucco, Carolina Cuello Oderiz   +2 more
doaj   +1 more source

Clinical Value of Metagenomic Next‐Generation Sequencing Versus Conventional Methods in Diagnosing Cryptococcal Infection After Kidney Transplantation

Organ Medicine, Volume 3, Issue 3, Page 130-138, September 2026.
This retrospective study evaluated metagenomic next‑generation sequencing (mNGS) against conventional methods (India ink, culture, antigen) for diagnosing cryptococcal infection in 16 kidney transplant recipients. mNGS showed a significantly higher positivity rate (93.8% vs 62.5%, p = 0.031) and shorter turnaround time (24 vs. 120 h, p < 0.001).
Luhao Liu, Rongxin Chen, Haonan Lin, Yuhe Guo, Guanghui Li, Jiali Fang, Zheng Chen   +6 more
wiley   +1 more source

When to consider an inborn error of immunity: clues for physicians

Internal Medicine Journal, Volume 56, Issue 9, Page 1488-1499, September 2026.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

Cryptococcus meningitis mimicking cerebral septic emboli, a case report series demonstrating injection drug use as a risk factor for development of disseminated disease

BMC Infectious Diseases, 2020
Background Clinicians may be less inclined to consider a diagnosis of cryptococcal meningitis in people without HIV infection or transplant-related immunosuppression. This may lead to a delay in diagnosis particularly if disseminated cryptococcal disease
Christopher Polk, Jacqueline Meredith, Alyssa Kuprenas, Michael Leonard   +3 more
doaj   +1 more source

Donor Dilemma: A National Simulation‐Based Case Curriculum for Teaching Donor Call Decision‐Making in Infectious Diseases Trainees

Transplant Infectious Disease, Volume 28, Issue 5, September/October 2026.
An asynchronous donor‐call case‐based progressive disclosure curriculum was feasible and valued across diverse ID and TID training programs. ID and TID trainees reported improved confidence in their clinical reasoning and ability to evaluate donor‐suitability, supporting this educational approach to address a training gap.
Robert Sean Tyler, Rachel B. Colven, Alexandra G. Mills, Drew W. Charles, Ruth O. Adekunle, Divisha Sharma, Yosra Alkabab, Scott R. Curry, Ricardo M. La Hoz, Courtney E. Harris   +9 more
wiley   +1 more source

De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi, Alastair G. McEwan, Ulrike Kappler   +2 more
wiley   +1 more source

Cryptococcal meningitis among perinatally HIV‐infected adolescents: Case series on presentation and management challenges

Clinical Case Reports, 2023
Diagnosis and management of cryptococcal meningitis in HIV‐infected adolescents is challenging in poor resource settings. A high index of suspicion based on clinical presentation is critical for early identification and treatment.
Peter Puplampu, Isabella Asamoah, Bismark O. Asare, Kofi P. Berko, Oluwakemi Oladele, Emmanuella Amankwa, Frempong Lambert, Antoinette T. Afriyie, Vincent Ganu   +8 more
doaj   +1 more source

Gingival enlargement and dentition loss associated with disseminated Cryptococcus neoformans infection in a dog

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract A 1‐year‐old, female, spayed, mixed‐breed dog was examined by a referring veterinarian for a 1‐week history of sneezing, bilateral mucoid nasal discharge, mild bilateral ocular discharge and stertor. During rhinoscopy, a plant awn foreign body was removed, but upper respiratory signs persisted. Computed tomography of the head revealed findings
Glynn Woods, Allison Volk, Janny Evenhuis, Abbie Metcalfe, Jane E. Sykes   +4 more
wiley   +1 more source

HIV–associated Cryptococcal Meningitis

, 2018
The DREAMM education programme and all related training materials are intended for health care workers (HCWs) based/working in low and middle income countries (LMICs) across Africa. The DREAMM education programme aims to increase the knowledge of HCWs to
Saulos Nyirenda (11927083), Charles Kouanfack (117476), Anne-Marie Reid (12474506), Angela Loyse (292490), Muirgen Stack (4396471), Cecilia Kanyama (504116), Aude Sturny Leclere (6028591), Timothée Boyer-chammard (6028590), Olivier Lortholary (69522), Sokoine L. Kivuyo (8918000), Lauriane Fomete Nome (12474503), Tom Harrison (6029911), Sayoki G. Mfinanga (13922038)   +12 more
core   +1 more source

Disseminated Cryptococcosis under Fingolimod Therapy

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Sven C. Engler, Morna F. Schmidt, Ana Ortins‐Pina, David Kluwig, Amir S. Yazdi   +4 more
wiley   +1 more source