Results 81 to 90 of about 13,630 (218)

Trends in Meningitis Burden and Projections to 2040: A Secondary Analysis of the Global Burden of Disease Study 2023

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Meningitis remains a global health challenge, characterized by substantial regional and etiologic disparities. This study aimed to analyze recent trends, forecast future burden, and examine the influence of development status on meningitis outcomes.
Mehdi Azizmohammad Looha, Ali Saberi Shahrbabaki, Fatemeh Masaebi, Mahmoud Zamani, Farid Zayeri   +4 more
wiley   +1 more source

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications

Advanced Science, Volume 13, Issue 17, 23 March 2026.
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan, Tao Luo, Yu Lin, Xiao‐Jun Wu, Wen‐Kang Shen, Jie Chen, Qian Lei, An‐Yuan Guo   +7 more
wiley   +1 more source

Cryptococcal meningitis complicating sarcoidosis

, 2016
Cryptococcal meningitis is an uncommon but severe complication of sarcoidosis. We present 2 patients with cryptococcal meningitis complicating sarcoidosis and compared findings with 38 cases reported in the literature.
Leonhard, Sonja E., Fritz, Daan, Brouwer, Matthijs C., van de Beek, Diederik   +3 more
core   +1 more source

CircRNA-1806 Decreases T Cell Apoptosis and Prolongs Survival of Mice After Cryptococcal Infection by Sponging miRNA-126

Frontiers in Microbiology, 2020
CircRNAs are a recently well-known regulator that mediates a variety of biological processes. Cryptococcus neoformans is an environmental fungal pathogen that can cause fatal cryptococcal meningitis in immunocompromised individuals.
Lei Zhang, Lei Zhang, Keming Zhang, Keming Zhang, Wenjie Fang, Wenjie Fang, Hang Li, Hang Li, Yingfang Li, Yingfang Li, Weiwei Jiang, Weiwei Jiang, Dongying Hu, Dongying Hu, Carolina Coelho, Xiaogang Liu, Xiaogang Liu, Liangqi Cai, Wanqing Liao, Wanqing Liao, Weihua Pan, Weihua Pan   +21 more
doaj   +1 more source

Experiences of HIV–Related Stigma and Mental Illness Among HIV–Associated Meningitis Patients in Rural Uganda

Brain and Behavior, Volume 16, Issue 2, February 2026.
Meningitis patients living with HIV often struggle with medication adherence and seeking HIV care due to the lack of education, support, and HIV‐related stigma, which can contribute to the development of mental health conditions in some individuals.
Abigail Link, Sarah Iribarren, Paul Bohjanen, Mark Okwir, David Meya, Betty Nabongo, Danuta Kasprzyk   +6 more
wiley   +1 more source

Acute Toxicity and Genotoxicity of cMoL, a Lectin From Moringa oleifera Seeds With Antifungal Activity Against Cryptococcus Strains

Journal of Applied Toxicology, Volume 46, Issue 2, Page 682-696, February 2026.
ABSTRACT Coagulant Moringa oleifera lectin (cMoL) is one of the compounds involved in the application of M. oleifera seeds for traditional water treatment methods. The present study highlights the new biotechnological potential of cMoL lectin as an antifungal agent against Cryptococcus neoformans B3501 and H99 and Cryptococcus gattii R265 strains ...
Matheus Cavalcanti de Barros, Sávia Soraia Santana da Silva, Eduarda Pinto Gagliano, Alícia Natalie Silva dos Santos, Leydianne Leite de Siqueira Patriota, Gustavo Ramos Salles Ferreira, Pollyanna Michelle da Silva, Simone da Paz Leôncio Alves, Julliano Matheus de Lima Maux, Jacinto da Costa Silva Neto, Fernanda Rafaelly Nascimento de Santana, Fabiana Aparecida Cavalcante Silva, Marilene Henning Vainstein, Luana Cassandra Breitenbach Barroso Coelho, Thâmarah de Albuquerque Lima, Thiago Henrique Napoleão, Patrícia Maria Guedes Paiva   +16 more
wiley   +1 more source

Risk factors for invasive Cryptococcus neoformans diseases: a case-control study.

PLoS ONE, 2015
BackgroundCryptococcus neoformans is a ubiquitous environmental fungus that can cause life-threatening meningitis and fungemia, often in the presence of acquired immunodeficiency syndrome (AIDS), liver cirrhosis, diabetes mellitus, or other medical ...
Ying-Ying Lin, Stephanie Shiau, Chi-Tai Fang   +2 more
doaj   +1 more source

Treatment of experimental cryptococcal meningitis with fluconazole: impact of dose and addition of flucytosine on mycologic and pathophysiologic outcome

, 1996
Fluconazole is effective in the therapy of cryptococcal meningitis in patients with AIDS. The optimal dosage of fluconazole and the impact of combination with flucytosine are not known.
Kartalija, M, Kaye, K, Täuber, MG, Tureen, JH, Liu, Q, Elliott, BR, Sande, MA   +6 more
core   +1 more source

Multiple Cranial Nerve Involvement In Cryptococcal Meningitis

Annals of Indian Academy of Neurology, 2000
Cryptococcal meningitis is an uncommon cause of multiple cranial nerve palsies. This case report illustrates one such case of cryptococcal meningitis clinically manifesting with extensive cranial nerve involvement in an HIV seronegative individual ...
Mahadevan A, Kumar A, Santosh V, Satishchandra P, Shankar S.K   +4 more
doaj  

Cerebrovascular injury in cryptococcal meningitis

, 2017
Background Cryptococcal meningitis continues to be one of the common causes of chronic central nervous system infection worldwide. Individuals with cryptococcal meningitis can occasionally present with small vessel vasculitis causing infarcts primarily ...
Anu Anna George, Reka Karuppusami, Sunithi Mani, Vanjare Harshad Arvind, Divya Muliyil, Ronald Albert Benton Carey, Cijoy K Kuriakose, Samuel George Hansdak, Ajay Kumar Mishra   +8 more
core   +1 more source