The small molecule (molecular mass <900 Daltons) composition of extracellular vesicles (EVs) produced by the pathogenic fungus Cryptococcus gattii is unknown, which limits the understanding of the functions of cryptococcal EVs.
Flavia C. G. Reis +7 more
doaj +1 more source
Microevolutionary traits and comparative population genomics of the emerging pathogenic fungus Cryptococcus gattii [PDF]
Emerging fungal pathogens cause an expanding burden of disease across the animal kingdom, including a rise in morbidity and mortality in humans. Yet, we currently have only a limited repertoire of available therapeutic interventions.
Angelini C +7 more
core +4 more sources
Cryptococcus neoformans and Cryptococcus gattii, the Etiologic Agents of Cryptococcosis [PDF]
Cryptococcus neoformans and Cryptococcus gattii are the two etiologic agents of cryptococcosis. They belong to the phylum Basidiomycota and can be readily distinguished from other pathogenic yeasts such as Candida by the presence of a polysaccharide capsule, formation of melanin, and urease activity, which all function as virulence determinants ...
Kwon-Chung, Kyung J. +6 more
openaire +3 more sources
Genome Variation in
Cryptococcus gattii recently emerged as the causative agent of cryptococcosis in healthy individuals in western North America, despite previous characterization of the fungus as a pathogen in tropical or subtropical regions.
C. A. D’Souza +40 more
doaj +1 more source
Conflicting interests in the pathogen-host tug of war : fungal micronutrient scavenging versus mammalian nutritional immunity [PDF]
Funding: The authors are supported by the European Research Council (STRIFE project funded on grant number ERC-2009-AdG-249793, http://erc.europa.eu). AJPB is also supported by the Wellcome Trust (grant numbers 080088, 097377, www.wellcome.ac.uk) and the
Ballou, Elizabeth R +3 more
core +2 more sources
Cryptococcal meningitis : epidemiology and therapeutic options [PDF]
Cryptococcal meningitis causes morbidity and mortality worldwide. The burden of disease is greatest in middle- and low-income countries with a high incidence of human immunodeficiency virus (HIV infection. Patients taking immunosuppressive drugs and some
Parris, Victoria, Sloan, Derek J.
core +1 more source
Cryptococcus gattii infection causing fulminant intracranial hypertension [PDF]
Cryptococcus neoformans variety gattii (C. gattii) causes infection in predominantly immunocompetent individuals. The majority of cases present with headache due to meningitis and its natural history normally follows an indolent course. We report a fatal case of fulminant cryptococcaemia culminating in severe intracranial hypertension due to C. gattii.
J, Bromilow, T, Corcoran
openaire +2 more sources
Cryptococcus neoformans var. gattii in Australia [PDF]
An examination of 45 clinical isolates of Cryptococcus neoformans revealed an unusually high incidence of C. neoformans var. gattii in South Australia (65%) and in the Northern Territory (95%). In assessing all the available data from Australian isolates of C. neoformans, there appeared to be an endemic focus for the incidence of C.
openaire +2 more sources
Pulmonary cryptococcal infection presenting with multiple lung nodules
Pulmonary infections from the environmental fungus Cryptococcus gattii (C. gattii) are notable for cryptococcomas, which are usually solitary and can be very large. As with infections with Cryptococcus neoformans (C.
Thilini L. Basnayake +2 more
doaj +1 more source
AIDS Patient Death Caused by Novel Cryptococcus neoformans × C. gattii Hybrid
Interspecies hybrids of Cryptococcus neoformans and C. gattii have only recently been reported. We describe a novel C. neoformans × C. gattii hybrid strain (serotype AB) that was previously described as C.
Marjan Bovers +6 more
doaj +1 more source

