Gene, virulence and related regulatory mechanisms in Cryptococcus gattii
Cryptococcus gattii is a kind of basidiomycetous yeast, which grows in human and animal hosts. C. gattii has four distinct genomes, VGI/AFLP4, VGII/AFLP6, VGIII/AFLP5, and VGIV/AFLP7. The virulence of C.
Huang Yemei +8 more
doaj +1 more source
First contemporary case of human infection with Cryptococcus gattii in Puget Sound: Evidence for spread of the Vancouver Island outbreak [PDF]
We report a case of cryptococcosis due to C. gattii which appears to have been acquired in the Puget Sound region, Washington State. Genotyping confirmed identity to the predominant Vancouver Island genotype.
Bartlett, K. +6 more
core +1 more source
Cryptococcus gattii, Florida, USA, 2011
To the Editor: Cryptococcosis is a systemic mycosis most commonly caused by 2 species of encapsulated yeast: Cryptococcus neoformans and C. gattii. C. gattii is a globally emerging pathogen. In the United States, an outbreak of C. gattii infection caused by molecular type VGII has been ongoing since 2004, primarily in the Pacific Northwest (1).
Rajesh Kunadharaju +4 more
openaire +2 more sources
Prospective data of a large randomized multi‐international leukaemia trial revealed an incidence of 1.1% of invasive yeast infections (IYIs) in children with acute lymphoblastic leukaemia. IYIs occurred predominantly during induction chemotherapy, presented as bloodstream infection ± tissue involvement, were due to a variety of yeast and had an ...
Andreas H. Groll +14 more
wiley +1 more source
Cryptococcal transmigration across a model brain blood-barrier: Evidence of the Trojan horse mechanism and differences between Cryptococcus neoformans var. grubii strain H99 and Cryptococcus gattii strain R265 [PDF]
© 2015 Institut Pasteur. Cryptococcus neoformans (. Cn) and Cryptococcus gattii (Cg) cause neurological disease and cross the BBB as free cells or in mononuclear phagocytes via the Trojan horse mechanism, although evidence for the latter is indirect ...
Combes, V +7 more
core +1 more source
Projecting Global Occurrence ofCryptococcus gattii
Cryptococcus gattii and C. neoformans cause pulmonary and systemic cryptococcosis. Recently, C. gattii was recognized as a distinct pathogen of humans and animals. We analyzed information from 400 publications (1948-2008) to examine whether the fungus occurs globally. Known distribution of C.
Deborah J. Springer, Vishnu Chaturvedi
openaire +3 more sources
ABSTRACT Background Meningoencephalitis causes significant morbidity and mortality in children worldwide. Prompt diagnosis remains challenging, yet advances in molecular diagnostic technology have improved diagnostic performance. This study examined whether the introduction of the BioFire FilmArray meningitis/encephalitis (ME) multiplex panel impacted ...
Louisa Mary Churcher +4 more
wiley +1 more source
Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation [PDF]
Cryptococcus neoformans is a pathogenic basidiomycetous yeast responsible for more than 600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties (i.e. grubii and neoformans, respectively).
et al, +3 more
core +9 more sources
Background Infection, even outbreak, caused by Cryptococcus gattii (C. gattii) has been reported in Canada and the United States, but there were sparsely-reported cases of C. gattii in China. Our interest in occurrence, clinical manifestation, laboratory
Liang Jin +6 more
doaj +1 more source
Population Genetic Analysis Reveals a High Genetic Diversity in the Brazilian Cryptococcus gattii VGII Population and Shifts the Global Origin from the Amazon Rainforest to the Semi-arid Desert in the Northeast of Brazil. [PDF]
Cryptococcus neoformans and Cryptococcus gattii are responsible globally for almost one million cryptococcosis cases yearly, mostly in immunocompromised patients, such as those living with HIV. Infections due to C.
Ana C P Souto +17 more
doaj +1 more source

