Results 71 to 80 of about 9,711 (215)

Diagnostic Performance of the QIAstat‐Dx Meningitis/Encephalitis Panel: Insights From Seven Clinical Evaluations

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
This review compares the QIAstat‐Dx ME panel with the BioFire FilmArray ME panel across seven studies on CNS infections. The findings support the clinical utility of QIAstat‐Dx, highlighting its diagnostic performance, interpretative advantages, and the need for further real‐world evaluation in high‐risk populations.
Flora Marzia Liotti, Brunella Posteraro, Maurizio Sanguinetti, Giulia De Angelis   +3 more
wiley   +1 more source

Treatment of Cryptococcus gattii Infection Using Voriconazole.

Internal medicine (Tokyo, Japan), 2021
We previously reported a 39-year-old man who presented with pulmonary and cerebral Cryptococcus gattii (genotype VGIIa) infection and was successfully treated with liposomal amphotericin B and flucytosine induction therapy. Following induction therapy, oral fluconazole treatment was initiated as consolidation therapy. However, the patient complained of
Nakao, Makoto, Fujita, Kohei, Arakawa, Sousuke, Hayashi, Shuntaro, Tomita, Saori, Sato, Hidefumi, Muramatsu, Hideki   +6 more
openaire   +2 more sources

Cryptococcus gattii, No Longer an Accidental Pathogen? [PDF]

Current Fungal Infection Reports, 2012
Cryptococcus gattii is an environmentally occurring pathogen that is responsible for causing cryptococcosis marked by pneumonia and meningoencephalitis in humans and animals. C. gattii can form long-term associations with trees and soil resulting in the production of infectious propagules (spores and desiccated yeast).
Deborah J, Springer, Sujal, Phadke, Blake, Billmyre, Joseph, Heitman   +3 more
openaire   +2 more sources

Neglected Mycoses in Brazil: A Population‐Based Study of Mortality and In‐Hospital Mortality Over 25 Years

Mycoses, Volume 69, Issue 2, February 2026.
ABSTRACT Objective To describe the epidemiology, associated factors, spatial distribution, and temporal trends of mortality and in‐hospital mortality related to systemic mycoses in Brazil, 2000–2024. Methods This is a nationwide ecological study combining temporal and spatial analyses using death certificates (DC; underlying and/or associated causes ...
Anderson Fuentes Ferreira, Jorg Heukelbach, Eliana Amorim de Souza, Maria Aparecida Shikanai‐Yasuda, Lisandra Serra Damasceno, Fernanda Dockhorn Costa, Terezinha do Menino Jesus Silva Leitão, Helia Kawa, Alberto Novaes Ramos Jr.   +8 more
wiley   +1 more source

The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme [PDF]

, 2016
Cryptococcosis is a life-threatening disease often associated with HIV infection. Three Cryptococcus species CYP51 enzymes were purified and catalyzed the 14α-demethylation of lanosterol, eburicol, and obtusifoliol.
Garvey, Edward P., Hoekstra, William J., Kelly, Diane E., Kelly, Steven L., Nes, W. David, Parker, Josie E., Price, Claire L., Schotzinger, Robert J., Warrilow, Andrew G. S.   +8 more
core   +1 more source

Rapid Detection of Fungi in Nail Specimens Using Multi‐Tube Recombinase Polymerase Amplification Assay

Mycoses, Volume 69, Issue 2, February 2026.
ABSTRACT Background Conventional diagnostic methods for onychomycosis possess disadvantages related to limited sensitivity, extended turnaround times and strong reliance on operator expertise. Objectives To develop a molecular assay with high sensitivity and specificity for rapid detection of multiple fungal pathogens in nail specimens. Methods A multi‐
Rong Wu, Meirong Li, Weian Du, Zetao Chen, Songchao Yin, Ling Hu, Liyan Xi, Jing Zhang, Huaiqiu Huang   +8 more
wiley   +1 more source

Cryptococcus gattii induces a cytokine pattern that is distinct from other cryptococcal species. [PDF]

PLoS ONE, 2013
Understanding more about the host's immune response to different Cryptococcus spp. will provide additional insight into the pathogenesis of cryptocococcis. We hypothesized that the ability of C.
Teske Schoffelen, Maria-Teresa Illnait-Zaragozi, Leo A B Joosten, Mihai G Netea, Teun Boekhout, Jacques F Meis, Tom Sprong   +6 more
doaj   +1 more source

Essential metals at the host-pathogen interface : nutritional immunity and micronutrient assimilation by human fungal pathogens [PDF]

, 2015
AC and DW are supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 102549/Z/13/Z).Peer reviewedPublisher ...
Crawford, Aaron, Wilson, Duncan
core   +1 more source

What makesCryptococcus gattiia pathogen? [PDF]

FEMS Yeast Research, 2015
Cryptococcosis is an invasive fungal infection of humans and other animals, typically caused by the species Cryptococcus neoformans in patients with impaired immunity. However, there is growing recognition of the importance of the related species C. gattii in causing infections in apparently immunocompetent individuals.
Ewa Bielska, Robin C. May
openaire   +2 more sources

Fatal Outcome due to Disseminated Cryptococcosis in a Patient With HIVrequiring Veno‐Arterial Extracorporeal Membrane Oxygenation: A Case Report

Acute Medicine &Surgery, Volume 13, Issue 1, January/December 2026.
This report details a fatal case of fulminant disseminated cryptococcosis in a young male with undiagnosed HIV. He rapidly developed multi‐organ failure, refractory shock, and cardiac arrest. Autopsy revealed extensive myocardial cryptococcal infiltration and microemboli, suggesting a critical role in the acute refractory shock that led to his death ...
Taisei Sasamoto, Naoki Kawahara, Hiroki Matsui, Koji Morishita   +3 more
wiley   +1 more source