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Melanin and virulence in Cryptococcus neoformans
Current Opinion in Microbiology, 2000Melanin synthesis has been associated with virulence for the human pathogenic fungus Cryptococcus neoformans. Recent evidence indicates that C. neoformans cells synthesize melanin during infection and that this pigment protects the fungus against immune defense mechanisms.
Arturo Casadevall +2 more
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Cryptococcus neoformans Meningoencephalitis
New England Journal of Medicine, 2018Cryptococcus neoformans Meningoencephalitis A 36-year-old man presented to the emergency department with a 2 week-history of headache, photophobia, and fever. Gram’s staining and India ink staining of the cerebrospinal fluid revealed encapsulated yeast, and C. neoformans was identified on culture.
Ana Pérez-Ayala, Raul Recio
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Cryptococcus neoformans, Cryptococcus gattii: Serotypes in Venezuela
Mycopathologia, 2008Cryptococcus neoformans is one of the medically important yeast-like fungi. C. neoformans var. gatti has been made a species: C. gatti. In our country, there are few studies about these two species and their serotypes. The aim of this study was to determine the distribution of C. neoformans and C.
M. Dolande +6 more
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Biochemical variation of Cryptococcus neoformans
Mycopathologia, 1984Ninety-seven strains of Cryptococcus neoformans and C. bacillisporus were examined for 44 biochemical characters and the results were analyzed numerically. One phenon emerged at the 86% level of similarity when strains were clustered according to their M-similarity values. All strains grew in ten carbon sources (D-glucose, D-galactose, arbutin, maltose,
Rudolph Hugh +2 more
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The commensalism ofCryptococcus neoformans
Medical Mycology, 1973Cryptococcus neoformans, was isolated from 3 of 561 sputum specimens. The fungus was not recovered from 162 samples of saliva or 310 fecal specimens. These data document the rarity of isolation of C. neoformans from human material but establish that it may be a commensal of the human nasopharynx under circumstances.
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The capsular dynamics of Cryptococcus neoformans
Trends in Microbiology, 2006Cryptococcus neoformans is a soil-dwelling fungus that causes life-threatening illness in immunocompromised individuals and latently infects many healthy individuals. C. neoformans, unlike other human pathogenic fungi, is surrounded by a polysaccharide capsule that is essential for survival and enables C.
Diane C. McFadden +2 more
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Phenotypic switching in Cryptococcus neoformans
Microbes and Infection, 2002Cryptococcus neoformans strains exhibit considerable phenotype variability with regards to the capsular polysaccharide, sterol composition of the cell wall, and cell and colony morphology. Phenotypic changes can occur spontaneously during in vitro passage of strains or during chronic infection in vivo and may be associated with differences in virulence.
Bettina C. Fries +2 more
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The ultrastructure ofCryptococcus neoformans
Medical Mycology, 1971The capsule, cell wall, plasma membrane and nucleus, as well as other intracytoplasmic organelles of Cryptococcus neoformans were examined by electron microscopy. The capsule, sometimes thicker than cells, consisted of either coiled, intertwining microfibrils or dots; the dot-type appeared with or without radiating cilia-type filaments at the periphery.
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Endotoxic substance of cryptococcus neoformans
Mycopathologia et Mycologia Applicata, 1974In this study an endotoxic substance was extracted from the cells ofCryptococcus neoformans and the physicochemical and biological properties of this substance (Cr-ET) were investigated. In comparison with endotoxin of gram-negative bacteria, the lethality of Cr-ET for mice and chick embryos was low and such biological activities were weak as the ...
Nobuo Kato +2 more
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