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Functional insight into cyclin-dependent kinase (CDK)7 via chemical inhibition of the priority fungal pathogen Cryptococcus neoformans

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Pooja Sethiya   +13 more
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Cryptococcus neoformans

2012
Cryptococcosis is caused by 2 varieties of Cryptococcus neoformans: Cryptococcus neoformans var neoformans (serotypes A and D) and Cryptococcus neoformans var gatti (serotypes B and C). Serotypes A and D are found worldwide, mostly in avian droppings. Serotypes B and C are found in tropical and subtropical countries in association with eucalyptus trees.
Shimon Kusne, Ann E McCullough
openaire   +1 more source

Cryptococcus neoformans Meningoencephalitis

New England Journal of Medicine, 2018
Cryptococcus neoformans Meningoencephalitis A 36-year-old man presented to the emergency department with a 2 week-history of headache, photophobia, and fever. Gram’s staining and India ink staining of the cerebrospinal fluid revealed encapsulated yeast, and C. neoformans was identified on culture.
Raul, Recio, Ana, Perez-Ayala
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Phosphoproteome of Cryptococcus neoformans

Journal of Proteomics, 2014
Cryptococcus neoformans is an encapsulated pathogenic yeast, which causes life threatening meningitis in immunocompromised individuals. C. neoformans var. grubii is the most prevalent and virulent form among the two varieties of C. neoformans - C. neoformans var. grubii and C. neoformans var. neoformans. The virulence of C.
Lakshmi Dhevi N, Selvan   +10 more
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Epidemiology of Cryptococcus neoformans

Mycopathologia, 1978
The concept of the epidemiology of Cryptococcus neoformans as the causative agent of cryptococcosis and as a basidiomycetous yeast is based on the fact that bird manure has been until now its only known habitat but not plant material which likewise harbours various nonpathogenic Cryptococcus species.
F, Staib   +5 more
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Cryptococcus neoformans, Cryptococcus gattii: Serotypes in Venezuela

Mycopathologia, 2008
Cryptococcus neoformans is one of the medically important yeast-like fungi. C. neoformans var. gatti has been made a species: C. gatti. In our country, there are few studies about these two species and their serotypes. The aim of this study was to determine the distribution of C. neoformans and C.
C, Pérez   +6 more
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Cryptococcus neoformans variety gattii

Medical Mycology, 2001
Cryptococcus neoformans var. gattii is emerging as a primary human pathogen which is distinct genetically and biochemically from C. neoformans var. neoformans. There is increasing evidence that it should be reclassified as a separate species within the Tremellales. In nature, C. n. var.
openaire   +2 more sources

Drug resistance in Cryptococcus neoformans

Drug Resistance Updates, 1999
Cryptococcus neoformans has become a major opportunistic fungal pathogen worldwide. Successful treatment of invasive disease with this fungus has used amphotericin B, flucytosine and various azoles. However, treatment failures continue to occur for a variety of reasons including direct antifungal drug resistance.
John R., Perfect, Gary M., Cox
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Phospholipase activity in Cryptococcus neoformans

Mycopathologia, 1996
Phospholipases have only been detected in a few fungi and yeasts, in particular in Candida albicans. Secreted phospholipases are considered by some researchers to be a potential factor of virulence and pathogenicity in C. albicans. Twenty-three Cryptococcus neoformans strains were tested in order to observe phospholipase production.
V, Vidotto   +5 more
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