Results 121 to 130 of about 729,903 (294)

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

Advanced Science, Volume 12, Issue 47, December 18, 2025.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera, Suneesh Thilak, Asha Patel, Prashant Nasa, Zubair Ahmed, Lorraine Jacques, William J. Scotton, Cyril Chacko, Randeep Mullhi, Ruoling Chen, Vikram Patil, Suresh Renukappa, Tonny Veenith   +12 more
wiley   +1 more source

Debatable issues in automated ECG reporting [PDF]

, 2017
Although automated ECG analysis has been available for many years, there are some aspects which require to be re-assessed with respect to their value while newer techniques which are worthy of review are beginning to find their way into routine use.
Abächerli, Roger, Albert, David E., Drew, Barbara, Hodges, Morrison, Kligfield, Paul, Macfarlane, Peter W., Mason, Jay W., Sommargren, Claire E., van Dam, Peter   +8 more
core   +1 more source

A meta-analysis of the effectiveness and safety of occlusion of patent foramen ovale versus pharmacological treatment for the prevention of recurrent cryptogenic stroke [PDF]

, 2023
Chen Chen, Xiaoli Yang, Yunzhi Shen, L M Wang, Yiming Gao, Jing Miao   +5 more
openalex   +1 more source

Immune Inflammation at the Crossroads of Atherosclerosis and Ischemic Stroke: Mechanisms, Trends, and Translational Perspectives

CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
As requested, we provide the graphical abstract text below. Once approved, we will insert it into the manuscript (Word file):“This review outlines the immune–inflammatory interactions linking atherosclerosis and ischemic stroke, highlights emerging mechanistic pathways, and summarizes potential translational targets across both vascular diseases ...
Hongdong Hao, Dian Chen, Cheng Qian, Xuanyi Zhou, Xi Peng, Guanlin Wang, Jingjing Tang, Hai‐Xin Liu   +7 more
wiley   +1 more source

Diagnostic Utility of N-Terminal Pro-B-Type Natriuretic Peptide in Identifying Atrial Fibrillation Post-Cryptogenic Stroke: A Systematic Review and Meta-Analysis

Pathophysiology
Background: Atrial fibrillation (AF) significantly contributes to acute ischemic stroke, with undetected AF being a common culprit in cryptogenic strokes.
Jay Patel, Sonu M. M. Bhaskar
doaj   +1 more source

Intracranial Hemorrhage Due to Secondary Hypertension from Intracranial Large Vessel Occlusion [PDF]

, 2020
Simultaneous hemorrhagic and ischemic strokes have been previously reported in the literature. Typically, these occur in patients secondary to dialysis, cerebral amyloid angiopathy, or thrombotic thrombocytopenic purpura.1,2,3 However, this is the unique
Khan, Asif A., Rawal, Amit, Saeed, Omar, Waldman, Alex   +3 more
core  

Standard complete blood count to predict long‐term outcomes in febrile infection–related epilepsy syndrome (FIRES): A multicenter study

Epilepsia, Volume 66, Issue 12, Page 4780-4794, December 2025.
Abstract Objective We investigated whether complete blood count (CBC) analyses during intensive care unit stay could predict 12‐month outcomes in patients with cryptogenic febrile infection–related epilepsy syndrome (FIRES), a subset of new‐onset refractory status epilepticus (NORSE).
Martin Guillemaud, Aurélie Hanin, James J. Riviello, Mario Chavez, Ayush Batra, Megan Berry, Francesca Bisulli, Carlos Castillo‐Pinto, Carla Cobos‐Hernandez, Sophie Demeret, Krista Eschbach, Raquel Farias‐Moeller, Madeline Fields, Nicolas Gaspard, Elizabeth E. Gerard, Teneille E. Gofton, Margaret T. Gopaul, Matthew D. Gruen, Anthony D. Jimenez, Karnig Kazazian, Minjee Kim, Marwa Mansour, Lara Marcuse, Clémence Marois, Mikaela Morales, Lorenzo Muccioli, Elena Pasini, Michelle M. Pham, Santiago Philibert Rosas, Aaron F. Struck, Nathan Torcida, Mark S. Wainwright, Ji Yeoun Yoo, Eyal Muscal, Vincent Navarro, Lawrence J. Hirsch, Yichen Lai   +36 more
wiley   +1 more source

Cardioverting acute atrial fibrillation and the risk of thromboembolism: not all patients are created equal [PDF]

, 2017
Current guidelines support the well-established clinical practice that patients who present with atrial fibrillation (AF) of less than 48 hours duration should be considered for cardioversion, even in the absence of pre-existing anticoagulation. However,
Rankin, Alastair J., Rankin, Stephen H.
core   +1 more source

Algorithm Improvements in an Insertable Cardiac Monitor Reduce False Positives and Episode Review Burden

Pacing and Clinical Electrophysiology, Volume 48, Issue 12, Page 1337-1343, December 2025.
Improvements to Insertable Cardiac Monitor (ICM) algorithms and nocturnal programming settings reduce the occurrence of false positives and non‐actionable arrhythmia detections. ABSTRACT Introduction The use of insertable cardiac monitors (ICM) for arrhythmia monitoring continues to grow steadily. However, ICM performance remains less than perfect, and
Mark Richards, Molly Kupfer, Keith Herrmann, Deepa Mahajan, David Perschbacher, Abhijit Rajan, Vasanth Ravikumar, Martin Burke   +7 more
wiley   +1 more source

Embolic stroke of unknown source (ESUS) in patients with atrial septum defect and patent foramen ovale: difference and similarities [PDF]

, 2015
Introduction Paradoxical embolism from right-to-left shunt through a patent foramen ovale (PFO) is a well-characterized cause of embolic strokes of undetermined source (ESUS).
DELABAYS, C.
core