Results 41 to 50 of about 14,401 (247)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Owing to the emergence and rapid advances of new-generation information and digitalization technologies, the concept of model-driven digital twin has received widespread attentions and is developing vigorously.
Jiaxing Guo +5 more
doaj +1 more source
Efficient High-Order Masking of FrodoKEM’s CDT-Based Gaussian Sampler
FrodoKEM is a conservative lattice-based KEM based on the Learning With Errors problem. While it was not selected for NIST standardization, it remains a strong candidate for high-security applications and is recommended by several national agencies ...
Elie Eid +3 more
doaj +1 more source
This short survey article reviews progress in asymmetric (or public-key) cryptography. Knapsack methods are described along with the successful attacks by Shamir and others. The RSA method and certain generalisations are also considered.
openaire +2 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Intent vulnerabilities pose a significant threat as they allow attackers to exploit unverified intent messages, leading to sensitive data leaks, privilege escalations, or unauthorized actions that compromise user privacy and system security.
Zhanhui Yuan +4 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Circuit-noise-resilient virtual distillation
Quantum error mitigation (QEM) is vital for improving quantum algorithms’ accuracy on noisy near-term devices. A typical QEM method, called Virtual Distillation (VD), can suffer from imperfect implementation, potentially leading to worse outcomes than ...
Xiao-Yue Xu +4 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source

