Results 71 to 80 of about 14,401 (247)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

A bimodal lattice-based linearly homomorphic signature for chain-based implicit data storage scheme

Discover Computing
As the demand for cross-domain collaborative verification grows in fields such as healthcare and industrial Internet of Things, achieving secure and efficient verification of heterogeneous data has become a critical challenge.
Ruifeng Li, Tanping Zhou, Yiliang Han, Xiaoliang Che, Xiaoyuan Yang   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Multi - Domain HEVC video steganography based on invertible neural network

Journal of King Saud University: Computer and Information Sciences
Most existing research on High Efficiency Video Coding (HEVC) video steganography is based on the premise that the receiver can acquire an unaltered bitstream.
Hemin Yin, Yingnan Zhang, Jun Li, Yanzhe Zhang, Min Shi   +4 more
doaj   +1 more source

A Hierarchical Authorization Reversible Data Hiding in Encrypted Image Based on Secret Sharing

Mathematics
In the current distributed environment, reversible data hiding in encrypted domain (RDH-ED) cannot grant corresponding privileges according to users’ identity classes.
Chao Jiang, Minqing Zhang, Yongjun Kong, Zongbao Jiang, Fuqiang Di   +4 more
doaj   +1 more source

Designing Hardware for Cryptography and Cryptography for Hardware

Proceedings of the 2022 ACM SIGSAC Conference on Computer and Communications Security, 2022
Devadas, Srinivas, Langowski, Simon, Samardzic, Nikola, Servan-Schreiber, Sacha, Sanchez, Daniel   +4 more
openaire   +3 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Survey of privacy-preserving data aggregation schemes in smart grid

Journal of King Saud University: Computer and Information Sciences
With the rapid advancement of technology, smart grid are increasingly replacing traditional grids. Smart grid offer efficient data management and analysis tools that significantly benefit users, but they also introduce new privacy challenges.
Yiliang Han, Yuanyuan Wang, Liqiang Wu, Haokang Feng, Xuguang Wu, Ruifeng Li   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source