Results 91 to 100 of about 70,877 (261)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
EEFDA: enabling efficient and fault-tolerant data aggregation scheme without TA in smart grid
Smart grid can be effectively enhanced by user data, however, data breaches pose significant risks related to privacy violations and data misuse. To address this issue, fault-tolerant privacy-preserving data aggregation schemes can protect data privacy ...
Yuanyuan Wang +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Cryptography and elliptic curves: a path through modern mathematics and its worldwide daily hidden use [PDF]
openMoving from an historical introduction of cryptography and the theory of elliptic curves useful in cryptography, we reach its nowadays widespread use all over the wold, especially on the https protocol, underlying the involvement of modern algebra ...
POZZA, GIULIO
core
Security-Mediated Certificateless Cryptography [PDF]
We introduce the notion of security-mediated certificateless (SMC) cryptography. This allows more lightweight versions of mediated cryptography while maintaining the ability for instantaneous revocation of keys.
Gonzalez Nieto, Juan M. +5 more
core +1 more source
Multimodal sarcasm detection aims to identify ironic intent from textual and visual information, with the core challenge lying in capturing semantic inconsistencies between different modalities.
Yaxuan Wang +4 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Survey of privacy-preserving data aggregation schemes in smart grid
With the rapid advancement of technology, smart grid are increasingly replacing traditional grids. Smart grid offer efficient data management and analysis tools that significantly benefit users, but they also introduce new privacy challenges.
Yiliang Han +5 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source

