Results 111 to 120 of about 70,877 (261)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
07021 Abstracts Collection – Symmetric Cryptography [PDF]
, 2007 From .. to .., the Dagstuhl Seminar 07021 ``Symmetric Cryptography'' automatically was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl.
Biham, Eli +3 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Backdoors in cryptography [PDF]
Diese Arbeit besteht aus zwei Teilen. Im ersten Teil erfolgt eine Systematisierung von Backdoors für kryptografische Verfahren, welche nur für den Angreifer effizient vom originalen Verfahren unterschieden werden können. Hierbei werden bereits bekannte Backdoors verallgemeinert, indem die Einbettung von Informationen getrennt von der Ausnutzung durch ...
openaire +2 more sources
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
GAN-based pseudo random number generation optimized through genetic algorithms
Complex & Intelligent SystemsPseudo-random number generators (PRNGs) are deterministic algorithms that generate sequences of numbers approximating the properties of random numbers, which are widely utilized in various fields.
Xuguang Wu +4 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
whyoleg/cryptography-kotlin: 0.3.1
<ul> <li>Fix concurrency issue in jdk provider (<a href="https://github.com/whyoleg/cryptography-kotlin/pull/26">#26</a>).
Oleg Yukhnevich, emeasure-github-private
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source