Results 121 to 130 of about 70,877 (261)

A Secure Data Sharing Model Utilizing Attribute-Based Signcryption in Blockchain Technology

Sensors
With the rapid development of the Internet of Things (IoT), the scope of personal data sharing has significantly increased, enhancing convenience in daily life and optimizing resource management.
Chaoyue Song, Lifeng Chen, Xuguang Wu, Yu Li   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Higher-order learning for fairness: a reinforcement learning framework for equitable and efficient influence maximization

Journal of King Saud University: Computer and Information Sciences
In the governance of online public opinion, the challenge of maximizing influence increasingly requires the simultaneous optimization of both dissemination breadth and fairness among groups.
Peijun Guo, Huan Li, Xinyue Mo
doaj   +1 more source

Privacy-Enhanced Stable Federated Learning for Statistically Heterogeneous Geospatial Data

Information
To address statistical heterogeneity and update-level privacy risks in federated learning for geospatial data, this paper proposes a hierarchically decoupled collaborative framework that integrates client-side privacy perturbation with server-side ...
Yiqi Sun, Keer Zhang, Chenxu Liu, Hezheng Lan, Hong Lei   +4 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Quantum Cryptography: a view from classical cryptography

, 2017
Much of digital data requires long-term protection of confidentiality, for example, medical health records. Cryptography provides such protection. However, currently used cryptographic techniques such as Diffe-Hellman key exchange may not provide long ...
Braun, Johannes, Johannes Buchmann, Demirel, Denise, Denise Demirel, Matthias Geihs, Geihs, Matthias, Johannes Braun, Buchmann, Johannes   +7 more
core   +1 more source

Mitigating Crossfire Attacks via Topology Spoofing Based on ENRNN-MTD

Applied Sciences
Crossfire attacks disrupt network services by targeting critical links of server groups, causing traffic congestion and server failures that prevent legitimate users from accessing services.
Dexian Chang, Xiaobing Zhang, Jiajia Sun, Chen Fang   +3 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source