Maternal and Paternal Risk Factors for Cryptorchidism and Hypospadias: A Case–Control Study in Newborn Boys [PDF]
Little is known on environmental risk factors for cryptorchidism and hypospadias, which are among the most frequent congenital abnormalities. The aim of our study was to identify risk factors for cryptorchidism and hypospadias, with a focus on potential ...
Alex Burdorf+8 more
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Defective spermatogenesis: Martin et al. respond [PDF]
This is an Open Access article - Copyright @ National Institute of Environmental Health Science.BACKGROUND: Male reproductive tract abnormalities such as hypospadias and cryptorchidism, and testicular cancer have been proposed to comprise a common ...
Boobis, Alan R.+5 more
core +2 more sources
Genomic copy number variation association study in Caucasian patients with nonsyndromic cryptorchidism [PDF]
Copy number variation (CNV) is a potential contributing factor to many genetic diseases. Here we investigated the potential association of CNV with nonsyndromic cryptorchidism, the most common male congenital genitourinary defect, in a Caucasian ...
Abrams, Debra J.+17 more
core +1 more source
Phenotype-specific association of the TGFBR3 locus with nonsyndromic cryptorchidism [PDF]
PURPOSE: Based on a genome-wide association study of testicular dysgenesis syndrome showing a possible association with TGFBR3, we analyzed data from a larger, phenotypically restricted cryptorchidism population for potential replication of this signal.
Abrams, D+18 more
core +1 more source
Intrauterine exposure to mild analgesics during pregnancy and the occurrence of cryptorchidism and hypospadia in the offspring: The Generation R Study [PDF]
This article is available open access through the publisher’s website. Copyright @ 2012 The Authors.BACKGROUND - Recently, over-the-counter mild analgesic use during pregnancy has been suggested to influence the risk of reproductive disorders in the ...
A. Burdorf+34 more
core +1 more source
Novas perspectivas no diagnóstico do hipogonadismo pediátrico masculino: a importância do AMH como marcador de células de Sertoli [PDF]
Sertoli cells are the most active cell population in the testis during infancy and childhood. In these periods of life, hypogonadism can only be evidenced without stimulation tests, if Sertoli cell function is assessed.
Grinspon, Romina, Rey, Rodolfo Alberto
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An unexpected long-term complication of genital burn in a child: Secondary cryptorchidism [PDF]
Genital and perineal burns are rare and challenging injuries with serious long-term complications. Involvement of the testes is a sign of severity. There is limited knowledge in the literature about the management of complications and testes involvement ...
Deliağa, H.+3 more
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Exposure to polychlorinated biphenyls and hexachlorobenzene, semen quality and testicular cancer risk [PDF]
PURPOSE: We carried out a case-control study to investigate the possible role of occupational and environmental exposure to endocrine disruptors in the onset of testicular cancer (TC). METHODS: We evaluated 125 TC patients and 103 controls.
CATTARUZZA, Maria Sofia+7 more
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Male reproductive health and environmental xenoestrogens [PDF]
EHP is a publication of the U.S. government. Publication of EHP lies in the public domain and is therefore without copyright. Research articles from EHP may be used freely; however, articles from the News section of EHP may contain photographs or ...
A Giwercman+89 more
core +2 more sources
Occurrence of testicular microlithiasis in androgen insensitive hypogonadal mice [PDF]
<b>Background</b>: Testicular microliths are calcifications found within the seminiferous tubules. In humans, testicular microlithiasis (TM) has an unknown etiology but may be significantly associated with testicular germ cell tumors ...
AC Peterson+24 more
core +2 more sources