Basic and Clinical Andrology, 2019 Résumé Contexte La non descente des testicules chez les garçons cryptorchides qui présentent une mini-puberté défectueuse et un taux réduit de testostérone (T) ont des gonocytes incapables de se différencier normalement en spermatogonie Ad.
Katharina Gegenschatz-Schmid +3 more
doaj +1 more source
Novas perspectivas no diagnóstico do hipogonadismo pediátrico masculino: a importância do AMH como marcador de células de Sertoli [PDF]
, 2011 Sertoli cells are the most active cell population in the testis during infancy and childhood. In these periods of life, hypogonadism can only be evidenced without stimulation tests, if Sertoli cell function is assessed.
Grinspon, Romina, Rey, Rodolfo Alberto
core +2 more sources
On the descent of the epididymo-testicular unit, cryptorchidism, and prevention of infertility
Basic and Clinical Andrology, 2017 Résumé Cette revue complète traite en profondeur les progrès réalisés dans la compréhension des mécanismes moléculaires à la base de la cryptorchidie, une pathologie fréquente décrite pour la première fois aux environs de 1786 par John Hunter.
Faruk Hadziselimovic
doaj +1 more source
Investigation of the Protective Effects of Amlodipine on the Structure and Function of Testicular Tissue following Experimental Unilateral Cryptorchidism in Rats [PDF]
Iranian Journal of Veterinary Surgery, 2019 Objective- Cryptorchidism, common birth defect of the male genital tract, is one of the causes of fertility problems. The elevation of tissue temperature following of cryptorchidism could induce oxidative stress which influences the cellular and tissue ...
Saber Shahraki +3 more
doaj +1 more source
Exposure to polychlorinated biphenyls and hexachlorobenzene, semen quality and testicular cancer risk [PDF]
, 2015 PURPOSE: We carried out a case-control study to investigate the possible role of occupational and environmental exposure to endocrine disruptors in the onset of testicular cancer (TC). METHODS: We evaluated 125 TC patients and 103 controls.
CATTARUZZA, Maria Sofia +7 more
core +1 more source
Occurrence of testicular microlithiasis in androgen insensitive hypogonadal mice [PDF]
, 2009 <b>Background</b>: Testicular microliths are calcifications found within the seminiferous tubules. In humans, testicular microlithiasis (TM) has an unknown etiology but may be significantly associated with testicular germ cell tumors ...
AC Peterson +24 more
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Curative GnRHa treatment has an unexpected repressive effect on Sertoli cell specific genes
Basic and Clinical Andrology, 2018 Résumé Contexte L’hormone folliculostimulante et la testostérone stimulent les cellules de Sertoli pour soutenir la fonction et la différentiation des cellules germinales. Pendant la minipuberté, lorsque la gonadotrophine (GnRH) stimule les augmentations
Katharina Gegenschatz-Schmid +6 more
doaj +1 more source
Epigenetics, cryptorchidism, and infertility
Basic and Clinical Andrology, 2023 Background Cryptorchid boys with defective mini-puberty and impaired differentiation of Ad spermatogonia (high infertility risk) have altered expression of several genes encoding histone methyltransferases compared to patients with intact differentiation
Faruk Hadziselimovic +2 more
doaj +1 more source
Genomic copy number variation association study in Caucasian patients with nonsyndromic cryptorchidism [PDF]
, 2016 Copy number variation (CNV) is a potential contributing factor to many genetic diseases. Here we investigated the potential association of CNV with nonsyndromic cryptorchidism, the most common male congenital genitourinary defect, in a Caucasian ...
Abrams, Debra J. +17 more
core +1 more source
Phenotype-specific association of the TGFBR3 locus with nonsyndromic cryptorchidism [PDF]
, 2015 PURPOSE: Based on a genome-wide association study of testicular dysgenesis syndrome showing a possible association with TGFBR3, we analyzed data from a larger, phenotypically restricted cryptorchidism population for potential replication of this signal.
Abrams, D +18 more
core +1 more source