Defining stage-specific activity of potent new inhibitors of Cryptosporidium parvum growth in vitro [PDF]
, 2020 Currently, nitazoxanide is the only FDA-approved treatment for cryptosporidiosis; unfortunately, it is ineffective in immunocompromised patients, has varied efficacy in immunocompetent individuals, and is not approved in infants under 1 year of age ...
Funkhouser-Jones, Lisa J +2 more
core +2 more sources
Octaarginine Improves the Efficacy of Nitazoxanide against Cryptosporidium parvum
Pathogens, 2022 Cryptosporidiosis is an intestinal disease that affects a variety of hosts including animals and humans. Since no vaccines exist against the disease till date, drug treatment is the mainstay of disease control. Nitazoxanide (NTZ) is the only FDA-approved
Tran Nguyen-Ho-Bao +6 more
doaj +1 more source
Cryptosporidium parvum: an emerging occupational zoonosis in Finland
Acta Veterinaria Scandinavica, 2023 Background Cryptosporidiosis has increased in recent years in Finland. We aimed to identify risk factors for human cryptosporidiosis and to determine the significance of Cryptosporidium parvum as a causative agent.
Tuulia Enbom +5 more
doaj +1 more source
Modeling cryptosporidiosis in humans and cattle: Deterministic and stochastic approaches
Parasite Epidemiology and Control, 2023 Cryptosporidiosis is a zoonotic disease caused by Cryptosporidium. The disease poses a public and veterinary health problem worldwide. A deterministic model and its corresponding continuous time Markov chain (CTMC) stochastic model are developed and ...
Faraja Luhanda +2 more
doaj +1 more source
Disseminated Cryptosporidium infection in an infant with CD40L deficiency
IDCases, 2021 The protozoan Cryptosporidium affects the digestive tract of humans and animals. Cryptosporidiosis leads to diarrhoea mimicking a cholera-like course with dehydration and may even result in death in immunodeficient patients, as patients with hyper-IgM ...
Fleur Dupuy +4 more
doaj +1 more source
Foot and Mouth Epidemic Reduces Cases of Human Cryptosporidiosis in Scotland. [PDF]
, 2003 In Scotland, rates of cryptosporidiosis infection in humans peak during the spring, a peak that is coincident with the peak in rates of infection in farm animals (during lambing and calving time).
Jones, Keith +3 more
core +2 more sources
Prevalence and genetic characterization of Cryptosporidium spp. In diarrheic children from Gonbad Kavoos city, Iran [PDF]
, 2013 Background: Cryptosporidium is an intestinal protozean parasite causing water-borne and foodborne outbreaks of diarrheal diseases. The present study was per-formed in order to find prevalence and subtypes of Cryptosporidium among children with diarrhea ...
Sharbatkhori, M. +4 more
core +3 more sources
Cryptosporidiosis Modulates the Gut Microbiome and Metabolism in a Murine Infection Model
Metabolites, 2021 Cryptosporidiosis is a major human health concern globally. Despite well-established methods, misdiagnosis remains common. Our understanding of the cryptosporidiosis biochemical mechanism remains limited, compounding the difficulty of clinical diagnosis.
Avinash V. Karpe +13 more
doaj +1 more source
Cryptosporidiosis and Filtration of Water from Loch Lomond, Scotland
Emerging Infectious Diseases, 2008 Previous evidence has suggested an association between consumption of unfiltered water from Loch Lomond, Scotland, and cryptosporidiosis. Before November 1999, this water had been only microstrained and disinfected with chlorine; however, since that time,
Kevin G.J. Pollock +3 more
doaj +1 more source
Effect of Caging on Cryptosporidium parvum Proliferation in Mice
Microorganisms, 2022 Cryptosporidiosis is an enteric infection caused by several protozoan species in the genus Cryptosporidium (phylum Apicomplexa). Immunosuppressed mice are commonly used to model this infection.
Hannah N. Creasey +2 more
doaj +1 more source