Results 41 to 50 of about 22,234 (173)

Molecular characterization and zoonotic risk assessment of Cryptosporidium spp. in Philippine bats

Food and Waterborne Parasitology
Cryptosporidium is a genus of parasitic protozoa known to cause diarrheal disease that impacts both humans and animals through infection of various vertebrate species.
Lin Xu, Yasuhiro Fukuda, Fumi Murakoshi, Phillip Alviola, Joseph Masangkay, Frances Cagayat Recuenco, Ayman Shehata, Tsutomu Omatsu, Hironori Bando, Hikaru Fujii, Yumi Une, Kentaro Kato   +11 more
doaj   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Husbandry factors are associated with skin, gastrointestinal and ophthalmic disorders in leopard geckos (Eublepharis macularius)

Veterinary Record, EarlyView.
Abstract Background Research into disorders in captive reptiles is notably sparse in the UK, despite the popularity of various species as pets. This study aimed to survey and investigate risk factors for disorders of leopard geckos in the UK. Methods Medical records for leopard geckos presenting at three veterinary practices between 2019 and 2023 were ...
Joshua Henley, Tom Dutton, Joanna Hedley
wiley   +1 more source

Putting Rodents at the Center of One Health Programs: A Narrative Synthesis

Integrative Zoology, EarlyView.
Rodents link human, animal, and environmental health across diverse ecosystems. Rodent diversity underpins both zoonotic disease risk and ecosystem function. Environmental change reshapes rodent communities and spillover dynamics. Rodents act as reservoirs, amplifiers, and sentinels of emerging pathogens.
Steven R. Belmain
wiley   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

When to consider an inborn error of immunity: clues for physicians

Internal Medicine Journal, EarlyView.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

Role of IFNγ in pathogenesis of SARS-CoV-2 infection

Медицинская иммунология, 2022
To date, there is no consensus explaining the relationship between varying concentrations of IFNγ and the severity of infection caused by SARS-CoV-2.
A. A. Artamonov, Yu. V. Nikitin, M. E. Meshkova, A. M. Ivanov   +3 more
doaj   +1 more source

Investigation of Cryptosporidium infection in a broad range of hosts in northern China

Parasites & Vectors
Background Cryptosporidium infection occurs in humans, domestic animals, and wildlife. To date, at least 49 species and 120 genotypes have been identified. Hitherto, molecular identification of Cryptosporidium species in wildlife has seldom been reported
Ziheng Liu, Jing Yang, Jiushikun Juman, Nannan Cui, Ligu Mi, Sándor Hornok, Guoyu Zhao, Quan Liu, Yuanzhi Wang   +8 more
doaj   +1 more source

Assessment of faecal calprotectin in neonatal calf diarrhoea using a human ELISA kit: Associations with faecal score and serum biochemical markers

Veterinary Record Open, Volume 13, Issue 2, December 2026.
Abstract Background Diarrhoea in newborn calves, which occurs in the first month of life and is caused by various pathogens, poses a significant threat to livestock industries. Therefore, timely diagnosis of enteritis in calves can be advantageous. Objective This study aimed to determine the efficacy of faecal calprotectin as a biomarker indicating ...
Narges Lotfalizadeh, Farima Jahromi, Alborz Yadollahi, Saeed Nazifi   +3 more
wiley   +1 more source

Molecular identification of Cryptosporidium spp. in alpacas (Vicugna pacos) in China

International Journal for Parasitology: Parasites and Wildlife, 2020
Cryptosporidium is a ubiquitous protozoan in human and animals. To investigate the genetic diversity of Cryptosporidium spp. in alpaca (Vicugna pacos) in China, 484 fecal samples from alpacas were collected at nine sites, and Cryptosporidium spp.
Qiyuan Zhang, Junqiang Li, Zhiguo Li, Chunyan Xu, Minyu Hou, Meng Qi   +5 more
doaj   +1 more source