Spontaneous Hepatobiliary Disease in a Breeding Colony of Aotus spp.
ABSTRACT Background Owl monkeys are nonhuman primate species in the genus Aotus. The Michale E. Keeling Center for Comparative Medicine and Research maintains an Owl Monkey Breeding and Research Resource composed of four species of owl monkeys: Aotus nancymai, A. vociferans, A. azarae, and A. griseimembra.
M. E. Hensel +4 more
wiley +1 more source
Simplified Linear Dose‐Response Models for Low‐Dose QMRAs
ABSTRACT This study analyzes widely used dose‐response (DR) models from potable reuse quantitative microbial risk assessments (QMRAs) to identify the low‐dose ranges where the log10‐transformed probability of infection and pathogen dose exhibit a linear relationship.
Katherine Crank +2 more
wiley +1 more source
Cryptosporidium Occultus in Disguise
As data accumulate in GenBank, the difficulties of delineating species of Cryptosporidium based on nuclear small subunit ribosomal RNA (ssu rRNA) gene information alone becomes increasingly evident. Here, we summarize currently available evidence suggesting that several ssu rDNA sequences primarily referred to as Cryptosporidium suis (some of them from
Rune Stensvold, Christen +9 more
openaire +4 more sources
Sequence differences in the diagnostic target region of the oocyst wall protein gene of Cryptosporidium parasites [PDF]
Nucleotide sequences of the Cryptosporidium oocyst wall protein (COWP) gene were obtained from Various Cryptosporidium spp. (C. wrairi, C. felis, C. meleagridis, C. baileyi, C. andersoni, C. muris, and C. serpentis) and C. parvum genotypes (human, bovine,
Sulaiman, I. +5 more
core
Molecular characterization of Cryptosporidium isolates from humans and other animals using random amplified polymorphic DNA analysis [PDF]
Genetic variation in 25 Cryptosporidium isolates was analyzed using the random amplified polymorphic DNA (RAPD) technique. Simple reproducible polymorphisms were generated (using five primers) from Cryptosporidium DNA that was free of contaminating ...
O'Donoghue, P. +17 more
core +1 more source
ABSTRACT Background and Aims Infections are recognized contributors to cancer development. This study aimed to assess the prevalence, socio‐demographic characteristics, and risk factors associated with intestinal protozoan parasites in patients with colorectal cancer (CRC) in Western Iran.
Alireza Moayyedkazemi +6 more
wiley +1 more source
Characterisation of Cryptosporidium growth and propogation in cell free environments [PDF]
Cryptosporidium is an enteric parasite that has a global impact on the health and survival of millions of people and animals worldwide. The resistant oocyst stage of the organism's life cycle is excreted in the faeces of infected animals and humans and ...
Estcourt, Annika
core
High‐Content CRISPR Screening: Methods and Applications
High‐content CRISPR screening represents a paradigm shift in functional genomics, moving beyond traditional survival‐based readouts to enable multidimensional mapping of genotype–phenotype relationships. This review systematically outlines the methodological evolution of this approach, detailing advances in perturbation modalities, delivery systems ...
Yike Zhang +6 more
wiley +1 more source
Cryptosporidium, Enterocytozoon, and Cyclospora Infections in Pediatric and Adult Patients with Diarrhea in Tanzania. [PDF]
Cryptosporidiosis, microsporidiosis, and cyclosporiasis were studied in four groups of Tanzanian inpatients: adults with AIDS-associated diarrhea, children with chronic diarrhea (of whom 23 of 59 were positive [+] for human immunodeficiency virus [HIV]),
Jorgensen, A F +13 more
core +1 more source
Multiplex PCR to Diagnose Gastrointestinal Infections: Key Limitations in Interpretation
ABSTRACT Multiplex polymerase chain reaction (PCR) panels are increasingly used for the evaluation of acute diarrhea, providing rapid and sensitive detection of a broad range of enteric pathogens. However, their widespread adoption has created important interpretive challenges for clinicians.
Giannoula S. Tansarli, Ferric C. Fang
wiley +1 more source

