Cultivation, cryopreservation, and transcriptomic studies of host-adapted Cryptosporidium parvum and Cryptosporidium hominis using enteroids [PDF]
iScienceSummary: Cryptosporidium hominis and Cryptosporidium parvum are major causes of severe diarrhea. Comparative studies of them are hampered by the lack of effective cultivation and cryopreservation methods, especially for C. hominis.
Miner Deng +12 more
doaj +5 more sources
Cryptosporidium parvum and Cryptosporidium hominis subtypes in crab-eating macaques [PDF]
Parasites & Vectors, 2019 Background Non-human primates are often infected with human-pathogenic Cryptosporidium hominis subtypes, but rarely with Cryptosporidium parvum. In this study, 1452 fecal specimens were collected from farmed crab-eating macaques (Macaca fascicularis) in ...
Li Chen +9 more
doaj +5 more sources
Cryptosporidium hominis Phylogenomic Analysis Reveals Separate Lineages With Continental Segregation [PDF]
Frontiers in Genetics, 2021 Cryptosporidium is a leading cause of waterborne outbreaks globally, and Cryptosporidium hominis and C. parvum are the principal cause of human cryptosporidiosis on the planet.
Felipe Cabarcas +10 more
doaj +5 more sources
Evaluation of Next-Generation Sequencing Applied to Cryptosporidium parvum and Cryptosporidium hominis Epidemiological Study. [PDF]
Pathogens, 2022 Background. Nowadays, most of the C. parvum and C. hominis epidemiological studies are based on gp60 gene subtyping using the Sanger sequencing (SgS) method. Unfortunately, SgS presents the limitation of being unable to detect mixed infections. Next-Generation Sequencing (NGS) seems to be an interesting solution to overcome SgS limits. Thus, the aim of
Bailly E +10 more
europepmc +6 more sources
Multilocus Sequence Typing helps understand the genetic diversity of Cryptosporidium hominis and Cryptosporidium parvum isolated from Colombian patients. [PDF]
PLoS ONE, 2022 Multilocus Sequence Typing has become a useful tool for the study of the genetic diversity and population structure of different organisms. In this study, a MLST approach with seven loci (CP47, MS5, MS9, MSC6-7, TP14, and gp60) was used to analyze the ...
Johanna Uran-Velasquez +8 more
doaj +2 more sources
Microphysiological gut-on-chip enables extended in vitro development of Cryptosporidium hominis [PDF]
Frontiers in Cellular and Infection MicrobiologyIntroductionCryptosporidium hominis is the dominant Cryptosporidium species infecting humans, but most advances in developing robust in vitro culturing platforms for Cryptosporidium have utilised C. parvum.
Samantha Gunasekera +12 more
doaj +2 more sources
Common occurrence of Cryptosporidium hominis in asymptomatic and symptomatic calves in France. [PDF]
PLoS Neglected Tropical Diseases, 2018 Cryptosporidium spp. infections are the most frequent parasitic cause of diarrhea in humans and cattle. However, asymptomatic cases are less often documented than symptomatic cases or cases with experimentally infected animals.
Romy Razakandrainibe +7 more
doaj +2 more sources
Parasitoses intestinais de indígenas da comunidade Mapuera (Oriximiná, Estado do Pará, Brasil): elevada prevalência de Blastocystis hominis e encontro de Cryptosporidium sp e Cyclospora cayetanensis [PDF]
, 2009 Foi avaliada a ocorrência de parasitoses intestinais em indígenas da aldeia Mapuera (Oriximiná, Estado do Pará, Brasil). No contexto de apreciações congêneres, expressa contribuição para adequado conhecimento do assunto, significativo sob o ponto de ...
Jaila Dias Borges +3 more
openalex +5 more sources
PLoS ONE, 2019 BackgroundMultiplex molecular panels are relentlessly replacing conventional methods for the detection of enteric pathogens from stool samples in clinical and research laboratories. Here we evaluated four commercial multiplex real-time PCR assays for the
Silvia Paulos +5 more
doaj +3 more sources
High Frequency of Cryptosporidium hominis Infecting Infants Points to A Potential Anthroponotic Transmission in Maputo, Mozambique. [PDF]
Pathogens, 2021 Cossa-Moiane I +16 more
europepmc +3 more sources