Results 191 to 200 of about 42,111 (230)

An immunoinformatics analysis: design of a multi-epitope vaccine against Cryptosporidium hominis by employing heat shock protein triggers the innate and adaptive immune responses

Journal of Biomolecular Structure and Dynamics, 2023
Cryptosporidium hominis, an anthropologically transferred species in the Cryptosporidium genus, represents many clinical studies in several countries. Its growth in the recent decade is primarily owing to epidemiologic studies.
N. Pandya, Amit Kumar
semanticscholar   +1 more source

Subtyping of Nonhuman Primate-Adapted Cryptosporidium hominis in Macaca Fascicularis and Macaca mulatta in Yunnan Province, Southwestern China

Vector Borne and Zoonotic Diseases, 2023
Background: Cryptosporidium spp. are a type of protozoan parasite responsible for causing diarrheal illness worldwide. They infect a broad range of vertebrate hosts, including both non-human primates (NHPs) and humans.
Yue Zhang, Yang Zou, Yaqi Li, Ping-Ping Ma, Zhongli Liu, Shuai Wang, Xiao-Lin Sun   +6 more
semanticscholar   +1 more source

Cryptosporidium hominis

CABI Compendium, 2022
This datasheet on Cryptosporidium hominis covers Identity, Hosts/Species Affected.

semanticscholar   +1 more source

A multi-epitope vaccine candidate developed from unique immunogenic epitopes against Cryptosporidium hominis by utilizing an immunoinformatics-driven approach

Journal of Biomolecular Structure and Dynamics, 2022
An immunoinformatics-based strategy is being investigated to identify prospective multi-subunit vaccine candidates against Cryptosporidium hominis (C. hominis). We used a systematic technique based on protein structure to create a competent multi-subunit
N. Pandya, Ashok Kumar
semanticscholar   +1 more source

CRYPTOSPORIDIUM HOMINIS: EXPERIMENTAL CHALLENGE OF HEALTHY ADULTS

The American Journal of Tropical Medicine and Hygiene, 2006
Cryptosporidium hominis causes diarrhea in humans and has been associated with community outbreaks. This study describes the infectivity, illness, and serologic response after experimental challenge of 21 healthy adult volunteers with 10–500 C. hominis (TU502) oocysts.
Cynthia L, Chappell, Pablo C, Okhuysen, Rebecca, Langer-Curry, Giovanni, Widmer, Donna E, Akiyoshi, Sultan, Tanriverdi, Saul, Tzipori   +6 more
openaire   +2 more sources

An immunocompetent rat model of infection with Cryptosporidium hominis and Cryptosporidium parvum

International Journal for Parasitology, 2020
A major obstacle to developing vaccines against cryptosporidiosis, a serious diarrheal disease of children in developing countries, is the lack of rodent models essential to identify and screen protective immunogens. Rodent models commonly used for drug discovery are unsuitable for vaccine development because they either are purposefully ...
Denise Ann Dayao, Abhineet Sheoran, Alison Carvalho, Hongbin Xu, Gillian Beamer, Giovanni Widmer, Saul Tzipori   +6 more
openaire   +2 more sources

Biology, persistence and detection of Cryptosporidium parvum and Cryptosporidium hominis oocyst

Water Research, 2004
Cryptosporidium parvum and Cryptosporidium hominis are obligate enteric protozoan parasites which infect the gastrointestinal tract of animals and humans. The mechanism(s) by which these parasites cause gastrointestinal distress in their hosts is not well understood.
C M, Carey, H, Lee, J T, Trevors
openaire   +2 more sources

Characterisation of small double stranded RNA molecule in Cryptosporidium hominis, Cryptosporidium felis and Cryptosporidium meleagridis

Parasitology International, 2006
Coding regions of double stranded RNA molecules from 3 human faecal samples containing Cryptosporidium hominis, C. felis and C. meleagridis were characterised by sequencing and compared with that previously obtained for C. parvum. Sequences outside the coding regions were also obtained. Overall similarities of between 86% and 92% and between 86% and 93%
Francesca, Leoni, Chris I, Gallimore, Jonathan, Green, Jim, McLauchlin   +3 more
openaire   +2 more sources

Detection of Cryptosporidium parvum and Cryptosporidium hominis in human patients in Cairo, Egypt

Parasitology Research, 2011
Cryptosporidium is a significant cause of diarrheal disease in developing and industrialized nations. Cryptosporidium hominis and Cryptosporidium parvum are the main agents of cryptosporidiosis in humans. In Egypt, very little is known about genetic structure of Cryptosporidium spp.
Nour M, Abd El Kader, María-Alejandra, Blanco, Marwa, Ali-Tammam, Abd El Rahman B, Abd El Ghaffar, Ahmed, Osman, Nabila, El Sheikh, José Miguel, Rubio, Isabel, de Fuentes   +7 more
openaire   +2 more sources

A Genome‐Scale Metabolic Model of Cryptosporidium hominis

Chemistry & Biodiversity, 2010
AbstractThe apicomplexan Cryptosporidium is a protozoan parasite of humans and other mammals. Cryptosporidium species cause acute gastroenteritis and diarrheal disease in healthy humans and animals, and cause life‐threatening infection in immunocompromised individuals such as people with AIDS. The parasite has a one‐host life cycle and commonly invades
Niti, Vanee, Seth B, Roberts, Stephen S, Fong, Patricio, Manque, Gregory A, Buck   +4 more
openaire   +2 more sources