Results 21 to 30 of about 42,111 (230)

High Frequency of Cryptosporidium hominis Infecting Infants Points to A Potential Anthroponotic Transmission in Maputo, Mozambique. [PDF]

Pathogens, 2021
Cryptosporidium is one of the most important causes of diarrhea in children less than 2 years of age. In this study, we report the frequency, risk factors and species of Cryptosporidium detected by molecular diagnostic methods in children admitted to two
Cossa-Moiane I, Cossa H, Bauhofer AFL, Chilaúle J, Guimarães EL, Bero DM, Cassocera M, Bambo M, Anapakala E, Chissaque A, Sambo J, Langa JS, Manhique-Coutinho LV, Fantinatti M, Lopes-Oliveira LA, Da-Cruz AM, de Deus N.   +16 more
europepmc   +2 more sources

Microphysiological gut-on-chip enables extended in vitro development of Cryptosporidium hominis [PDF]

Frontiers in Cellular and Infection Microbiology
IntroductionCryptosporidium hominis is the dominant Cryptosporidium species infecting humans, but most advances in developing robust in vitro culturing platforms for Cryptosporidium have utilised C. parvum.
Samantha Gunasekera, Benjamin Thierry, Brendon King, Paul Monis, Jillian M. Carr, Abha Chopra, Mark Watson, Mark O’Dea, Edward Cheah, Ramesh Ram, Peta L. Clode, Nawal Hijjawi, Una Ryan   +12 more
doaj   +2 more sources

Long-Term Preservation and Storage of Faecal Samples in Whatman^® Cards for PCR Detection and Genotyping of Giardia duodenalis and Cryptosporidium hominis. [PDF]

Animals (Basel), 2021
Simple Summary Preservation and storage of biological samples prior to testing and analysis is a pressing issue in the epidemiological field studies conducted in remote or poor-resource areas with limited or no access to electricity where the cold chain ...
Köster PC, Bailo B, Dashti A, Hernández-Castro C, Calero-Bernal R, Ponce-Gordo F, González-Barrio D, Carmena D.   +7 more
europepmc   +2 more sources

Multiple introductions and recombination events underlie the emergence of a hyper-transmissible Cryptosporidium hominis subtype in the USA. [PDF]

Cell Host Microbe, 2023
Huang W, Guo Y, Lysen C, Wang Y, Tang K, Seabolt MH, Yang F, Cebelinski E, Gonzalez-Moreno O, Hou T, Chen C, Chen M, Wan M, Li N, Hlavsa MC, Roellig DM, Feng Y, Xiao L.   +17 more
europepmc   +2 more sources

Piperazine-Derivative MMV665917: An Effective Drug in the Diarrheic Piglet Model of Cryptosporidium hominis. [PDF]

J Infect Dis, 2019
BACKGROUND Cryptosporidiosis, an enteric protozoon, causes substantial morbidity and mortality associated with diarrhea in children 75% of diarrhea reported in these children.
Lee S, Ginese M, Girouard D, Beamer G, Huston CD, Osbourn D, Griggs DW, Tzipori S.   +7 more
europepmc   +2 more sources

Genetic Diversity of Cryptosporidium hominis in a Bangladeshi Community as Revealed by Whole-Genome Sequencing. [PDF]

J Infect Dis, 2018
In the developing world, Cryptosporidium is one of the top causes of infant diarrhea. In a Bangladesh community we have discovered that a substantial amount of genetic recombination and genetic polymorphism in surface proteins occurs in the ...
Gilchrist CA, Cotton JA, Burkey C, Arju T, Gilmartin A, Lin Y, Ahmed E, Steiner K, Alam M, Ahmed S, Robinson G, Zaman SU, Kabir M, Sanders M, Chalmers RM, Ahmed T, Ma JZ, Haque R, Faruque ASG, Berriman M, Petri WA.   +20 more
europepmc   +2 more sources

Persistent Occurrence of Cryptosporidium hominis and Giardia duodenalis Subtypes in a Welfare Institute. [PDF]

Front Microbiol, 2018
Few data are available on the transmission dynamics of intestinal protozoa in children in welfare institutes. In this study, fecal specimens were collected from 396 children in a welfare institute in Shanghai, China during December 2011 (207 specimens ...
Wang Y, Li N, Guo Y, Wang L, Wang R, Feng Y, Xiao L.   +6 more
europepmc   +2 more sources

Comparative performance evaluation of four commercial multiplex real-time PCR assays for the detection of the diarrhoea-causing protozoa Cryptosporidium hominis/parvum, Giardia duodenalis and Entamoeba histolytica.

PLoS ONE, 2019
BackgroundMultiplex molecular panels are relentlessly replacing conventional methods for the detection of enteric pathogens from stool samples in clinical and research laboratories. Here we evaluated four commercial multiplex real-time PCR assays for the
Silvia Paulos, José María Saugar, Aida de Lucio, Isabel Fuentes, María Mateo, David Carmena   +5 more
doaj   +2 more sources

Molecular prevalence and subtyping of Cryptosporidium hominis among captive long-tailed macaques (Macaca fascicularis) and rhesus macaques (Macaca mulatta) from Hainan Island, southern China

Parasites & Vectors, 2019
Background Cryptosporidium is an important zoonotic parasite that is commonly found in non-human primates (NHPs). Consequently, there is the potential for transmission of this pathogen from NHPs to humans.
Wei Zhao, Huanhuan Zhou, Hairong Jin, Meicen Liu, Mingyan Qiu, Lihua Li, Feifei Yin, Jasper Fuk-Woo Chan, Gang Lu   +8 more
doaj   +2 more sources

The therapeutic efficacy of azithromycin and nitazoxanide in the acute pig model of Cryptosporidium hominis. [PDF]

PLoS One, 2017
Recent reports highlighting the global significance of cryptosporidiosis among children, have renewed efforts to develop control measures. We have optimized the gnotobiotic piglet model of acute diarrhea to evaluate azithromycin (AZR), nitazoxanide (NTZ),
Lee S, Harwood M, Girouard D, Meyers MJ, Campbell MA, Beamer G, Tzipori S.   +6 more
europepmc   +2 more sources