Results 11 to 20 of about 24,991 (221)

Novel lactate dehydrogenase inhibitors with in vivo efficacy against Cryptosporidium parvum.

PLoS Pathogens, 2019
Cryptosporidium parvum is a highly prevalent zoonotic and anthroponotic protozoan parasite that causes a diarrheal syndrome in children and neonatal livestock, culminating in growth retardation and mortalities. Despite the high prevalence of C.
Kun Li, Sara M Nader, Xuejin Zhang, Benjamin C Ray, Chi Yong Kim, Aditi Das, William H Witola   +6 more
doaj   +2 more sources

Exploration of Zoo felids in North-East China for the prevalence and molecular identification of Cryptosporidium spp. [PDF]

PeerJ, 2021
Cryptosporidium spp. is a protozoan having the potential to cause zoonosis in humans and animals. Despite the zoonotic importance of this protozoan parasite, limited data are available about its prevalence in zoo felids in North-Eastern China. Hence, the
Shakeel Hussain, Syed Mohsin Bukhari, Lixin Wang, Nimra Khalid, Zhijun Hou   +4 more
doaj   +2 more sources

Genetic diversity of Cryptosporidium spp. in non-human primates in rural and urban areas of Ethiopia

PLoS ONE, 2022
Non-Human Primates (NHPs) harbor Cryptosporidium genotypes that can infect humans and vice versa. NHPs Chlorocebus aethiops and Colobus guereza and humans have overlapping territories in some regions of Ethiopia, which may increase the risk of zoonotic ...
Ambachew W. Hailu, Abraham Degarege, Beyene Petros, Damien Costa, Yonas Yimam Ayene, Ven-ceslas Villier, Abdelmounaim Mouhajir, Loic Favennec, Romy Razakandrainibe, Haileeysus Adamu   +9 more
doaj   +2 more sources

The Cryptosporidium parvum Kinome [PDF]

BMC Genomics, 2011
Hundreds of millions of people are infected with cryptosporidiosis annually, with immunocompromised individuals suffering debilitating symptoms and children in socioeconomically challenged regions at risk of repeated infections. There is currently no effective drug available.
Artz, Jennifer D, Wernimont, Amy K, Allali-Hassani, Abdellah, Zhao, Yong, Amani, Mehrnaz, Lin, Yu-Hui, Senisterra, Guillermo, Wasney, Gregory A, Fedorov, Oleg, King, Oliver, Roos, Annette, Lunin, Vlad V, Qiu, Wei, Finerty, Patrick, Hutchinson, Ashley, Chau, Irene, von Delft, Frank, MacKenzie, Farrell, Lew, Jocelyne, Kozieradzki, Ivona, Vedadi, Masoud, Schapira, Matthieu, Zhang, Chao, Shokat, Kevan, Heightman, Tom, Hui, Raymond   +25 more
openaire   +5 more sources

Prevalence and molecular characterization of Cryptosporidium in goats across four provincial level areas in China. [PDF]

PLoS ONE, 2014
This study assessed the prevalence, species and subtypes of Cryptosporidium in goats from Guangdong Province, Hubei Province, Shandong Province, and Shanghai City of China. Six hundred and four fecal samples were collected from twelve goat farms, and the
Rongsheng Mi, Xiaojuan Wang, Yan Huang, Peng Zhou, Yuxuan Liu, Yongjun Chen, Jun Chen, Wei Zhu, Zhaoguo Chen   +8 more
doaj   +1 more source

Distribution and genetic characterizations of Cryptosporidium spp. in pre-weaned dairy calves in Northeastern China's Heilongjiang Province. [PDF]

PLoS ONE, 2013
BACKGROUND: Cryptosporidium spp. are common parasites of humans and animals. Farm animals, especially pre-weaned calves, are considered to be one of main animal reservoir hosts of Cryptosporidium in the transmission of human cryptosporidiosis. The aim of
Weizhe Zhang, Rongjun Wang, Fengkun Yang, Longxian Zhang, Jianping Cao, Xiaoli Zhang, Hong Ling, Aiqin Liu, Yujuan Shen   +8 more
doaj   +1 more source

Identification of zoonotic Cryptosporidium parvum in freshwater ornamental fish

Journal of Zoonotic Diseases, 2020
Regarding the importance of zoonotic species of Cryptosporidium in humans and domestic animals, and the lack of information about the distribution of Cryptosporidium spp.
Parisa Shahbazi , Najmeh Sheikhzadeh , Ahmad Nematollahi , Javad Ashrafi Helan   +3 more
doaj   +1 more source

Molecular identification of Cryptosporidium spp. in alpacas (Vicugna pacos) in China

International Journal for Parasitology: Parasites and Wildlife, 2020
Cryptosporidium is a ubiquitous protozoan in human and animals. To investigate the genetic diversity of Cryptosporidium spp. in alpaca (Vicugna pacos) in China, 484 fecal samples from alpacas were collected at nine sites, and Cryptosporidium spp.
Qiyuan Zhang, Junqiang Li, Zhiguo Li, Chunyan Xu, Minyu Hou, Meng Qi   +5 more
doaj   +1 more source

Molecular identification and antiprotozoal activity of silver nanoparticles on viability of Cryptosporidium parvum isolated from pigeons, pigeon fanciers and water

Scientific Reports, 2023
Cryptosporidium is a protozoan that causes acute gastroenteritis, abdominal pain, and diarrhea in many vertebrate species, including humans, animals and birds. A number of studies have reported the occurrence of Cryptosporidium in domestic pigeons. Thus,
Rasha M. M. Abou Elez, Amira S. A. Attia, Hala M. N. Tolba, Reham G. A. Anter, Ibrahim Elsohaby   +4 more
doaj   +1 more source

Fully resolved assembly of Cryptosporidium parvum [PDF]

GigaScience, 2021
Abstract Background Cryptosporidium parvum is an apicomplexan parasite commonly found across many host species with a global infection prevalence in human populations of 7.6%. Understanding its diversity and genomic makeup can help in fighting established infections and prohibiting further ...
Vipin K Menon, Pablo C Okhuysen, Cynthia L Chappell, Medhat Mahmoud, Medhat Mahmoud, Qingchang Meng, Harsha Doddapaneni, Vanesa Vee, Yi Han, Sejal Salvi, Sravya Bhamidipati, Kavya Kottapalli, George Weissenberger, Hua Shen, Matthew C Ross, Kristi L Hoffman, Sara Javornik Cregeen, Donna M Muzny, Ginger A Metcalf, Richard A Gibbs, Joseph F Petrosino, Fritz J Sedlazeck   +21 more
openaire   +4 more sources