Dislocation subgrain structures and modeling the plastic hardening of metallic single crystals [PDF]
A single crystal plasticity theory for insertion into finite element simulation is formulated using sequential laminates to model subgrain dislocation structures.
Bronkhorst, C. A. +2 more
core +1 more source
The standard way of modeling plasticity in polycrystals is by using the crystal plasticity model for single crystals in each grain, and imposing suitable traction and slip boundary conditions across grain boundaries.
Admal, Nikhil Chandra +2 more
core +1 more source
A three-dimensional multiscale model of intergranular hydrogen-assisted cracking [PDF]
We present a three-dimensional model of intergranular hydrogen-embrittlement (HE) that accounts for: (i) the degradation of grain-boundary strength that arises from hydrogen coverage; (ii) grain-boundary diffusion of hydrogen; and (iii) a continuum model
Ortiz, M., Rimoli, J. J.
core +1 more source
Cooperativity in plastic crystals
A statistical mechanical model previously adopted for the analysis of the α-relaxation in structural glass formers is rederived within a general theoretical framework originally developed for systems approaching the ideal glassy state. The interplay between nonexponentiality and cooperativity is reconsidered in the light of energy landscape concepts ...
Pieruccini M, Tombari E
openaire +3 more sources
Unraveling deformation mechanisms around FCC and BCC nanocontacts through slip trace and pileup topography analyses [PDF]
Nanocontact loadings offer the potential to investigate crystal plasticity from surface slip trace emissions and distinct pileup patterns where individual atomic terraces arrange into hillocks and symmetric rosettes.
Alcalá Cabrelles, Jorge +3 more
core +2 more sources
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Crystal plasticity model calibration for 316l stainless steel single crystals during deformation [PDF]
Type 316L austenitic stainless steel is an important structural material used for the in-core components and pressure boundaries of light water reactors.
Bogataj, Matej +2 more
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A multiscale constitutive model for intergranular stress corrosion cracking in type 304 austenitic stainless steel [PDF]
Intergranular stress corrosion cracking (IGSCC) is a fracture mechanism in sensitised austenitic stainless steels exposed to critical environments where the intergranular cracks extends along the network of connected susceptible grain boundaries.
Rahimi, S, Siddiq, A
core +2 more sources

