Results 41 to 50 of about 1,211,759 (244)

Crystal plasticity models accounting for twinning [PDF]

Computer Methods in Materials Science, 2013
Different approaches to account for twinning in crystal plasticity models are discussed. In particular, three main issues related to this mechanism of plastic deformation are addressed: modelling of texture evolution in the presence of twinning, impact ...
Katarzyna Kowalczyk-Gajewska
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

High-resolution simulating of grain substructure in cold rolling and its effects on primary recrystallization in annealing of ferritic stainless steel

Journal of Materials Research and Technology
In this study, an integrated crystal plasticity and cellular automaton (CA) model has been developed and employed to investigate the processes of cold rolling and annealing in ferritic stainless steel.
Kangjie Song, Haochen Ding, Chi Zhang, Liwen Zhang, Guanyu Deng, Huaibei Zheng   +5 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Extremum principle of crystal plasticity

, 1988
An analytical method for determining slip shear rate under prescribed stress rate or prescribed strain rate has been presented on the basis of the incremental theory of crystal plasticity.
Wang ZQ(王自强)
core   +2 more sources

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

A Combined Experimental-Numerical Approach for Investigating Texture Evolution of NiTi Shape Memory Alloy under Uniaxial Compression

Metals, 2017
Texture evolution of NiTi shape memory alloy was investigated during uniaxial compression deformation at 673 K (400 °C) by combining crystal plasticity finite element method with electron back-scattered diffraction experiment and transmission electron ...
Li Hu, Shuyong Jiang, Yanqiu Zhang
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Single crystal plasticity theories predicting bounded lattice rotation under simple shear deformation

Journal of the Mechanical Behavior of Materials, 2012
Up to now, models for single crystal plasticity predict unbounded lattice rotations under simple shear. Asaro et al. proposed a model that predicts bounded rotations as long as the viscosity parameters are appropriately chosen.
Broese Carsten, Tsakmakis Charalampos
doaj   +1 more source

A crystal plasticity FEM investigation of a Cu single crystal processed by accumulative roll-bonding

Journal of Materials Research and Technology, 2019
In this study, texture modelling of a copper single crystal processed by accumulative roll-bonding (ARB) was conducted for the first time. A crystal plasticity finite element method (CPFEM) model was developed, and the predicated textures were validated ...
Hui Wang, Cheng Lu, Kiet Tieu
doaj   +1 more source