Results 31 to 40 of about 1,211,759 (244)

Modelling of crystal plasticity effects on the crack initiation energies of a bi-crystal interface (Nb/ A120 3)

open access: yesComputer Assisted Methods in Engineering and Science, 2022
The present paper examines the crystal orientation effects on the energy at the crack-tip of niobium/ alumina joints. The analyses have been done using crystal plasticity theory.
Amir Siddiq, Siegfried Schmauder
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Ellipticity loss analysis for tangent moduli deduced from a large strain elastic–plastic self-consistent model [PDF]

open access: yes, 2009
In order to investigate the impact of microstructures and deformation mechanisms on the ductility of materials, the criterion first proposed by Rice is applied to elastic–plastic tangent moduli derived from a large strain micromechanical model combined ...
LORRAIN, Jean-Paul   +5 more
core   +1 more source

基于多尺度晶体塑性有限元的GCr15轴承钢拉-压不对称性研究

open access: yesJixie qiangdu, 2021
In this paper,stress triaxiality is added to the classical crystal plasticity constitutive model to investigate the experimental phenomenon of tension-compression asymmetry for the GCr15 bearing steel.Firstly, the crystal plasticity constitutive model is
樊冬, 余丰, 李淑欣
doaj  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

On the application of strain gradient crystal plasticity to study strain localization phenomena in single crystals [PDF]

open access: yes, 2021
Strain localization is an important plastic instability process occurring prior to fracture. It is usually observed in the form of narrow bands of intense plastic shear strain in deformed bodies undergoing severe inhomogeneous deformation.
CAI, Lei   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Crystal Plasticity Modeling of Mechanical Anisotropy for TiAl Alloy Under Uniaxial and Biaxial Loading

open access: yesCrystals
TiAl alloys are widely used in aerospace applications due to their low density and good mechanical properties. However, their pronounced mechanical anisotropy resulting from the preferred orientations of lamellar crystals remains an important issue. This
Wenya Peng   +7 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Study on the irradiation effect of mechanical properties of RPV steels using crystal plasticity model

open access: yesNuclear Engineering and Technology, 2019
In this paper a body-centered cubic(BCC) crystal plasticity model based on microscopic dislocation mechanism is introduced and numerically implemented.
Junfeng Nie   +3 more
doaj   +1 more source

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