Results 81 to 90 of about 589,086 (216)

HIC1 suppresses Tumor Progression and Enhances CD8+ T Cells Infiltration Through Promoting GSDMD‐induced Pyroptosis in Gastric Cancer

Advanced Science, EarlyView.
These findings elucidate the innovative role of HIC1 as a transcriptional activator in GC, driving the initiation of pyroptosis and enhancing CD8+ T cell infiltration, which has certain novelty and creative significance. Collectively, targeting HIC1 can present an appealing immunotherapeutic strategy to improve outcomes in GC patients.
Mengjie Kang, Wenqi Du, Lina Ding, Mengdi Wu, Dongsheng Pei   +4 more
wiley   +1 more source

Localized Sound‐Integrated Display Speaker Using Crosstalk‐Free Piezoelectric Vibration Array

Advanced Science, EarlyView.
To approach multisensory integration of speaker‐integrated OLED displays, this study investigates localized sound emission in display panel speakers by examining crosstalk‐free diaphragm vibrations and enhanced frequency response through multi‐arrayed piezoelectric exciters.
Inpyo Hong, Su Seok Choi
wiley   +1 more source

A Two‐Protein Chemoreceptor Complex Regulates Oxygen Thresholds in Bacterial Magneto‐Aerotaxis

Advanced Science, EarlyView.
Magnetotactic bacteria align with Earth's magnetic field, helping them migrate toward low‐oxygen environments. This study reveals how Magnetospirillum gryphiswaldense uses a specialized flavin adenine dinucleotide (FAD)‐dependent chemoreceptor, composed of two interacting proteins, for precise navigation in oxygen gradients.
Julian Herz, Carina Weigel, Leonie Scheder, Raz Zarivach, Itay Algov, Yonatan Chemla, Felix Popp, Cornelius Riese, Mohammad A. Charsooghi, Lital Alfonta, Michael M. Meijler, Dirk Schüler, Damien Faivre, Daniel Pfeiffer   +13 more
wiley   +1 more source

Role of Tunneling Nanotubes in Arachidonic Acid Transfer and Macrophage Function Reprogramming in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
Tunneling nanotubes facilitate the transfer of long‐chain fatty acids, primarily arachidonic acid, from tumor cells to macrophages, leading to lipid accumulation and activation of the PI3K‐Akt pathway. This drives a shift from the anti‐tumor CD5L⁺ phenotype to a pro‐tumor TREM2⁺ phenotype.
Meiru Chen, Shangyumeng Zhao, Xiaoli Xie, Jiaqi Wang, Miao Su, Lixian Zhang, Ruolin Cui, Dongqiang Zhao   +7 more
wiley   +1 more source

Pushing the Frontiers: Artificial Intelligence (AI)‐Guided Programmable Concepts in Binary Self‐Assembly of Colloidal Nanoparticles

Advanced Science, EarlyView.
Colloidal nanoparticles self‐assembly advances towards intelligent, customized assembly through precise control of binary co‐assemblies. This review explores the evolution from monolithic to binary assemblies, highlighting how the AI‐guided programmable assembly approach has the potential to shift from passive assembly to active intelligent design.
Cancan Li, Lindong Ma, Zhenjie Xue, Xiao Li, Shan Zhu, Tie Wang   +5 more
wiley   +1 more source

The development of an airborne instrumentation computer system for flight test [PDF]

Instrumentation interfacing frequently requires the linking of intelligent systems together, as well as requiring the link itself to be intelligent. The airborne instrumentation computer system (AICS) was developed to address this requirement.
Bever, G. A.
core   +1 more source

Laser‐Induced Co‐Doped FePS3 with Massively Phosphorus Sulfur Vacancies Nanosheet for Efficient and Highly Stable Electrocatalytic Oxygen Reaction

Advanced Science, EarlyView.
DFT‐guided defect engineering in 2D FePS3 reveals S/P vacancies Co‐doped and exposed Fe sites synergistically enhance OER performance. Laser‐ablation‐induced (Fe0.53Co0.46)PS3 exhibits excellent OER performance (288 mV overpotential, 58.3 mV dec−1 Tafel slope) and outstanding stability (138 h at 10 mA cm−2, 27h at 100 mA cm−2).
Ruiqi Xu, Guoshuai Fu, Weimi Ding, Yifan Li, Guowei Yang, Peng Yu, Shuang Li, Pu Liu   +7 more
wiley   +1 more source

Cross-language compiler benchmarking: are we fast yet?

Dynamic Languages Symposium, 2016
Stefan Marr, Benoit Daloze, H. Mössenböck   +2 more
semanticscholar   +1 more source

Ambipolar Charge Transport in Perovskite CsPbBr3 γ‐Ray Detectors with Superior Uniformity and Spectral Resolution by Zone Refining Processing

Advanced Science, EarlyView.
Zone refining processing has been proposed to achieve ultrahigh purity level in perovskite CsPbBr3 crystals, enabling ambipolar charge transport by enhancing the electron transport properties, thereby resulting in better γ‐ray detector performance with exceptional uniformity and reproducibility.
Bao Xiao, Yuquan Wang, Ning Ding, Haoming Qin, Nannan Shen, Xuchang He, Qihao Sun, Yihui He   +7 more
wiley   +1 more source

Novel ATR/PARP1 Dual Inhibitors Demonstrate Synergistic Antitumor Efficacy in Triple‐Negative Breast Cancer Models

Advanced Science, EarlyView.
Novel ATR/PARP1 dual inhibitors are developed for the first time. Advanced lead B8 effectively reduces cell viability in vitro and suppresses tumor growth in vivo, with better potency than ATRi and PARPi alone or in combination. Mechanistically, B8 induces apoptosis, arrests the cell cycle, and inhibits cancer cells colony formation, migration, and ...
Yuan Gao, Jiawei Zhou, Chen‐Chen Wang, Zong‐Hao Wang, Nian‐Dong Mao, Meng‐Lan He, Peng‐Peng Zhang, Ping Huang, Guo‐Wei Ye, Yu‐Qing Zhang, Feng‐Hui Tang, Hang Zhang, Tian Xie, Xiang‐Yang Ye   +13 more
wiley   +1 more source