Results 131 to 140 of about 622,957 (315)

Nogo Receptor crystal structures with a native disulfide pattern suggest a novel mode of self-interaction

, 2017
The Nogo Receptor (NgR) is a glycophosphatidylinositol-anchored cell-surface protein and is a receptor for three myelin-associated inhibitors of regeneration: myelin-associated glycoprotein, Nogo66 and oligodendrocyte myelin glyco­protein. In combination
Roderick P. Tas, Janssen, Bert J. C., Bert J. C. Janssen, Vlieg, Hedwich C., Hedwich C. Vlieg, Tas, Roderick P., Pronker, Matti F., Matti F. Pronker   +7 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Crystal structure generation with autoregressive large language modeling

Nature Communications
The generation of plausible crystal structures is often the first step in predicting the structure and properties of a material from its chemical composition.
Luis M. Antunes, Keith T. Butler, Ricardo Grau-Crespo   +2 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Improved machine learning framework for prediction of phases and crystal structures of high entropy alloys

Journal of Alloys and Metallurgical Systems
High-entropy alloys (HEAs) are gaining popularity because of their remarkable properties controlled by phases and crystal structures. In addition to that, in the field of material informatics, machine learning (ML) techniques have gained considerable ...
Debsundar Dey, Suchandan Das, Anik Pal, Santanu Dey, Chandan Kumar Raul, Pritam Mandal, Arghya Chatterjee, Soumya Chatterjee, Manojit Ghosh   +8 more
doaj   +1 more source

Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park, Emily J. Koubek, Richard Beare, Lynn Ang, Brian C. Callaghan, Rodica Pop‐Busui, Eva L. Feldman, Evan L. Reynolds   +7 more
wiley   +1 more source

Ferroelectricity-driven strain-mediated magnetoelectric coupling in two-dimensional multiferroic heterostructure

Nature Communications
In the post-Moore era, CMOS technology faces challenges in storage and power consumption. Two-dimensional van der Waals ferromagnets, with their atomically sharp interfaces, enable heterostructure with ferroelectric materials.
Chuanyang Cai, Yao Wen, Shiheng Liang, Lei Yin, Ruiqing Cheng, Hao Wang, Xiaoqiang Feng, Liang Liu, Jun He   +8 more
doaj   +1 more source

Cycloauration of pyridyl sulphonamides

, 2008
The pyridyl-2-alkylsulfonamides C₅H₄N(CH₂)nNHSO₂R (n = 1,2; R = Me, Ph or p-C₆H₄Me) and 8-(p-tosylamino)quinoline undergo facile cycloauration reactions with H[AuCl₄] in water, giving metallacyclic complexes coordinated through the pyridyl (or quinolyl ...
Nicholson, Brian K., Kilpin, Kelly Joan, Henderson, William   +2 more
core   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source

Non-volatile electric-field control of room-temperature ferromagnetism in Fe3GaTe2 heterostructures

Nature Communications
Van der Waals multiferroic structures hold promises for advancing the development of low-power multifunctional nanoelectronics devices, but single-phase two-dimensional multiferroic materials are limited.
Chuanyang Cai, Yao Wen, Lei Yin, Ruiqing Cheng, Hao Wang, Xiaoqiang Feng, Liang Liu, Chao Jiang, Jun He   +8 more
doaj   +1 more source