Results 31 to 40 of about 43,221 (257)
Imaging Cataract-Specific Peptides in Human Lenses
Cells, 2022 Age-related protein truncation is a common process in long-lived proteins such as proteins found in the ocular lens. Major truncation products have been reported for soluble and membrane proteins of the lens, including small peptides that can accelerate ...
Kevin L. Schey +3 more
doaj +1 more source
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia [PDF]
, 2003 Vascular endothelial growth factor (VEGF-A) is a major regulator of blood vessel formation and function. it controls several processes in endothelial cells, such as proliferation, survival, and migration, but it is not known how these are coordinately ...
Abramsson, A +10 more
core +2 more sources
Interaction of βA3-Crystallin with Deamidated Mutants of αA- and αB-Crystallins.
PLoS ONE, 2015 Interaction among crystallins is required for the maintenance of lens transparency. Deamidation is one of the most common post-translational modifications in crystallins, which results in incorrect interaction and leads to aggregate formation.
Ekta Tiwary +4 more
doaj +1 more source
Membranes, 2022 α-crystallin-membrane association increases with age and cataracts, with the primary association site of α-crystallin being phospholipids. However, it is unclear if phospholipids’ acyl chain length and degree of unsaturation influence α-crystallin ...
Geraline Trossi-Torres +2 more
doaj +1 more source
Endogenous bioelectric currents promote differentiation of the mammalian lens [PDF]
, 2018 Acknowledgements We are grateful to Kevin S. Mackenzie in our imaging core facility. This work was supported by the University of Aberdeen (at which the majority of the experimental work was conducted).
Andley +52 more
core +1 more source
Science, 1929 A method is described for the preparation of a crystalline protein from commercial pepsin preparations which has powerful peptic activity. The composition, optical activity, and proteolytic activity of this protein remain constant through seven successive crystallizations.
openaire +8 more sources
In vivo substrates of the lens molecular chaperones αA-crystallin and αB-crystallin.
PLoS ONE, 2014 αA-crystallin and αB-crystallin are members of the small heat shock protein family and function as molecular chaperones and major lens structural proteins.
Usha P Andley +2 more
doaj +1 more source
Beneficial effects of αB-crystallin in spinal cord contusion injury [PDF]
, 2012 αB-crystallin is a member of the heat shock protein family that exerts cell protection under several stress-related conditions. Recent studies have revealed that αB-crystallin plays a beneficial role in a mouse model of multiple sclerosis, brain ischemia,
David, Samuel +6 more
core +2 more sources
Frontiers in Marine Science, 2023 The eye of a cephalopod is a well-known example of convergent evolution and resembles the vertebrate eye. Although cephalopods and vertebrates exhibit similar eye form and function, they differ in visual origin and structure. The common long-arm octopus (
Kyoung-Bin Ryu +11 more
doaj +1 more source
Predicting protein decomposition: the case of aspartic-acid racemization kinetics [PDF]
, 1999 The increase in proportion of the non-biological (D-) isomer of aspartic acid (Asp) relative to the L- isomer has been widely used in archaeology and geochemistry as a tool for dating. The method has proved controversial, particularly when used for bones.
A. C. T. van Duin +24 more
core +3 more sources