Results 61 to 70 of about 43,221 (257)
Integrative Zoology, EarlyView.Protein processing in the endoplasmic reticulum is highlighted in response to heat stress in Platysternon megacephalum. Under heat stress, the up‐regulation of genes such as CHOP in protein processing in the endoplasmic reticulum pathway, along with the suppression of energy and lipid metabolism and the up‐regulation of JARID2 expression, leads to ...
Jian Hong +7 more
wiley +1 more source
Transcriptional profiling of single fiber cells in a transgenic paradigm of an inherited childhood cataract reveals absence of molecular heterogeneity. [PDF]
, 2019 Our recent single-cell transcriptomic analysis has demonstrated that heterogeneous transcriptional activity attends molecular transition from the nascent to terminally differentiated fiber cells in the developing mouse lens.
Bhat, Suraj P +6 more
core
Species Limits and Phylogeography of North American Cricket Frogs (Acris: Hylidae) [PDF]
, 2008 Cricket frogs are widely distributed across the eastern United States and two species, the northern cricket frog (Acris crepitans) and the southern cricket frog (A. gryllus) are currently recognized. We generated a phylogenetic hypothesis for Acris using
Berendzen, Peter B. +4 more
core +2 more sources
Radiopaque Crystalline, Non-Crystalline and Nanostructured Bioceramics
Materials, 2022 Radiopacity is sometimes an essential characteristic of biomaterials that can help clinicians perform follow-ups during pre- and post-interventional radiological imaging. Due to their chemical composition and structure, most bioceramics are inherently radiopaque but can still be doped/mixed with radiopacifiers to increase their visualization during or ...
Maziar Montazerian +10 more
openaire +3 more sources
Acta Ophthalmologica, EarlyView.Abstract Purpose To compare the inflammatory response in the eye after trabeculectomy to after phacoemulsification, focusing on anterior chamber flare (AC flare) and central macular thickness (CMT). Methods Data from 436 participants in two randomized controlled trials were analysed.
Yasmeen Ahmed +5 more
wiley +1 more source
Mutations in human αA-crystallin/sHSP affect subunit exchange interaction with αB-crystallin. [PDF]
PLoS ONE, 2012 Mutation in αA-crystallin contributes to the development of congenital cataract in humans. Heterooligomerization of αA-crystallin and αB-crystallin is essential for maintaining transparency in the eye lens.
Ilangovan Raju +2 more
doaj +1 more source
Mechanism of action of VP1-001 in cryAB(R120G)-associated and age-related cataracts [PDF]
, 2019 PurposeWe previously identified an oxysterol, VP1-001 (also known as compound 29), that partially restores the transparency of lenses with cataracts. To understand the mechanism of VP1-001, we tested the ability of its enantiomer, ent-VP1-001, to bind ...
Andley, Usha P. +10 more
core +2 more sources
Cell Biochemistry and Function, Volume 44, Issue 2, February 2026.ABSTRACT Living beings are persistently challenged by stress. Stress can be induced by internal stressors and external stressors. External stressors, including radiation, heat, heavy metals, nutritional imbalances, infections, and psychological stress, can induce protein denaturation, leading to misfolded or aggregated proteins.
Paka Sravan Kumar +5 more
wiley +1 more source
Impact of Subunit Composition on the Uptake of α-Crystallin by Lens and Retina. [PDF]
PLoS ONE, 2015 Misfolded protein aggregation, including cataract, cause a significant amount of blindness worldwide. α-Crystallin is reported to bind misfolded proteins and prevent their aggregation.
Niklaus H Mueller +5 more
doaj +1 more source
Roles of TGFβ and FGF signals during growth and differentiation of mouse lens epithelial cell in vitro. [PDF]
, 2017 Transforming growth factor β (TGFβ) and fibroblast growth factor (FGF) signaling pathways play important roles in the proliferation and differentiation of lens epithelial cells (LECs) during development.
Gong, Xiaohua +5 more
core +2 more sources