Results 71 to 80 of about 43,221 (257)

The Subgingival Host–Microbial Landscape in Mothers With Periodontitis and Their At‐Risk Offspring

Journal of Clinical Periodontology, Volume 53, Issue 2, Page 201-213, February 2026.
ABSTRACT Aim To evaluate the subgingival proteome and microbiome of mothers with periodontitis and their offspring, thereby assessing signatures of periodontal diseases. Methods Forty participants in four groups were included: mothers with periodontitis and their offspring, as well as periodontally healthy mothers and their offspring.
Hélvis E. S. Paz, Camila S. Stolf, Kai Bao, Mabelle F. Monteiro, Lucas M. Carvalho, Angelika Silbereisen, Georgios N. Belibasakis, Renato C. V. Casarin, Nagihan Bostanci   +8 more
wiley   +1 more source

Alpha B-crystallin is a new prognostic marker for laryngeal squamous cell carcinoma

Journal of Experimental & Clinical Cancer Research, 2012
Background Alpha B-crystallin (αB-crystallin) has been suggested to play an important role in the development of solid tumors. However, the association between αB-crystallin expression and clinicopathological characteristics of human laryngeal carcinoma ...
Mao Yuan, Zhang Da-Wei, Lin Hong, Xiong Lin, Liu Ying, Li Qing-Dong, Ma Jun, Cao Qing, Chen Ren-Jie, Zhu Jin, Feng Zhen-Qing   +10 more
doaj   +1 more source

Interactive domains in the molecular chaperone human alphaB crystallin modulate microtubule assembly and disassembly. [PDF]

PLoS ONE, 2007
Small heat shock proteins regulate microtubule assembly during cell proliferation and in response to stress through interactions that are poorly understood.Novel functions for five interactive sequences in the small heat shock protein and molecular ...
Joy G Ghosh, Scott A Houck, John I Clark
doaj   +1 more source

Cornea organoids from human induced pluripotent stem cells. [PDF]

, 2017
The cornea is the transparent outermost surface of the eye, consisting of a stratified epithelium, a collagenous stroma and an innermost single-cell layered endothelium and providing 2/3 of the refractive power of the eye. Multiple diseases of the cornea
Adams, Sheila M, Birk, David E, Chakravarti, Shukti, Foster, James W, Wahlin, Karl, Zack, Donald J   +5 more
core   +3 more sources

Mitochondrial Adaptation to Mechanical Stress in Cardiac Ageing and Disease

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Mechanical forces shape the heart's energy factories. This review explores how mitochondria in cardiac cells sense and respond to biomechanical stress, altering their structure, positioning, and metabolism. By linking mechanical cues to mitochondrial adaptation, the article highlights pathways driving heart disease and points to new strategies for ...
Aishwarya Prakash, Thomas Iskratsch
wiley   +1 more source

Unprecedented Nitrite‐Dependent Aromatic Amination to Synthesize 2,4‐Diamino‐3‐Hydroxybenzoic Acid

ChemBioChem, Volume 27, Issue 2, January 2026.
By comparing the biosynthetic gene clusters for natural products with 2,4‐diamino‐3‐hydroxybenzoic acid (2,4,3‐DAHBA) moiety and heterologous expression in Streptomyces albus, we identified nine genes required for the biosynthesis of 2,4,3‐DAHBA, including nitrite biosynthesis genes.
Ko Kuwabara, Yohei Katsuyama, Yasuo Ohnishi   +2 more
wiley   +1 more source

Influence of Thermal Perturbation of the Oligomeric Size of -Crystallin on its Chaperone Function – A Biophysical Study [PDF]

, 2010
-Crystallin is the major protein component of the vertebrate eye lens and is composed of two subunits A- and B-, 20 kDa each having 57% sequence homology between them. Both subunits associate to form large oligomer of 800 kDa average molecular weight. It
Laha, B
core  

Investigating the Role of Zebrafish Retinoschisin Homologs Rs1a and Rs1b During Retinal Development

Developmental Neurobiology, Volume 86, Issue 1, January 2026.
ABSTRACT Deficiency in the retinoschisin protein (RS1) causes X‐linked juvenile retinoschisis (XLRS), a retinal degenerative disease that disrupts retinal layers and forms cystic cavities. In addition to its structural function, RS1 is believed to play a role in retinal development.
Isa van der Veen, Céline Koster, Jacoline B. Ten Brink, Maarten Kamermans, Camiel J. F. Boon   +4 more
wiley   +1 more source

MAFG Induces the Methylation of CRYAB to Promote the Activation of A1 Astrocyte After Spinal Cord Injury

Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
All in all, silencing MAFG inhibited the activation of A1 astrocyte and neuroinflammation through regulating CRYAB methylation. ABSTRACT Purpose To investigate the effects of MAF bZIP transcription factor G (MAFG) on the transformation of A1/A2 reactive astrocytes and the production of inflammatory factors after spinal cord injury (SCI). Methods An SCI
Xuefei Li, Zhuang Zhu, Ying Wang, Hao Wan, Zhiwei Wang, Wanqing Qiao   +5 more
wiley   +1 more source

CRYβA3/A1-Crystallin Knockout Develops Nuclear Cataract and Causes Impaired Lysosomal Cargo Clearance and Calpain Activation. [PDF]

PLoS ONE, 2016
βA3/A1-crystallin is an abundant structural protein of the lens that is very critical for lens function. Many different genetic mutations have been shown to associate with different types of cataracts in humans and in animal models. βA3/A1-crystallin has
Shylaja Hegde, Robert A Kesterson, Om P Srivastava   +2 more
doaj   +1 more source