Results 41 to 50 of about 18,901 (265)
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Solutions of the scientific problem of modifying of foundry alloys
For a solution of the problem of modification of a microstructure of cast alloys it is necessary to accept admission that crystallization centers of crystals of phases are the crystalline buildups consisting of nanocrystals of phases.
E. I. Marukovich, V. Yu. Stetsenko
doaj +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Nanostructural theory of metal melts. Foundry production and metallurgy
It has been shown that atomic and atomic cluster theories cannot be the basis for theories of crystallization and modification of metals and alloys. Based on thermodynamic calculations, a nanostructural theory of metal melts has been developed.
E. I. Marukovich, V. Yu. Stetsenko
doaj +1 more source
Formation of microstructure of Bi-40 wt. % Sn alloy during hightspeed crystallization [PDF]
Rapidly solidified foils of Bi — 40 wt. % Sn have homogeneous distribution bismuth and tin phases with microcrystalline structure. Its formation is caused by the spinodal decay of supercooled supersaturated liquid solution and subsequent nucleation and ...
V.G. Shepelevich
doaj +1 more source
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
NANOSTRUCTURAL PROCESSES AT MELTING AND MOULDING OF SILUMINS
The existing theories of liquid state, crystallization and modifying don’t allow determining nanostructural physical and chemical mechanisms of melting and casting of silumins.
E. I. Marukovich, V. Y. Stetsenko
doaj
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source

