Combinatorial QD‐SiO2 nanoparticles combined with linear unmixing of the photoluminescence spectrum increase the multiplexity of assays. Linear unmixing spectral analysis is a technique where signals from tens of fluorophores can be deconvoluted to increase multiplexing by 4–5‐fold.
Yuwei Wang, Jennifer I. L. Chen
wiley +1 more source
Mass Spectrometry-Driven Epitope Mapping: Application of Diethylpyrocarbonate Covalent Labeling for the Immunotherapeutic Target Programmed Cell Death Protein 1. [PDF]
Ramanandana P +9 more
europepmc +1 more source
A customizable SERS‐based aptasensor platform integrates aptamer‐functionalized gold nanoparticles with machine learning models (RF and CNN) to detect tau protein, a key biomarker for Alzheimer's disease. This rapid, label‐free detection system achieves a detection limit of 100 pM, enabling early diagnosis and monitoring of disease progression.
Farbod Ebrahimi +4 more
wiley +1 more source
Introduction to the SAMPREP special issue. [PDF]
Gupta K.
europepmc +1 more source
Solution‐Based Biophysical Methods for Guiding Design of Aptamers into Electrochemical Biosensors
It is found that aptamer binding and folding thermodynamics measured via isothermal titration calorimetry and nano differential scanning calorimetry directly correlate with electrochemical aptamer‐based biosensor response. We show that these techniques report on the magnitude of conformational change and could be used as guides to help engineer ...
Minh‐Dat Nguyen +4 more
wiley +1 more source
Mechanochemical Synthesis and Electron Crystallography Characterization of van der Waals Lanthanoid 2D Metal-Organic Frameworks. [PDF]
Lorenzo F +9 more
europepmc +1 more source
Rational Design of a Foldon-Derived Heterotrimer Guided by Quantitative Native Mass Spectrometry. [PDF]
Liu X +4 more
europepmc +1 more source
Erratum: Crystal structure and Hirshfeld surface analysis of 1-[(benzyl-dimethyl-sil-yl)meth-yl]-1-ethyl-piperidin-1-ium ethane-sulfonate. Corrigendum. [PDF]
Kirchhoff JL +3 more
europepmc +1 more source
Present and future structural biology activities at DESY and the European XFEL. Erratum. [PDF]
Oberthür D +6 more
europepmc +1 more source

