Results 41 to 50 of about 662,036 (283)

Semax, a Copper Chelator Peptide, Decreases the Cu(II)-Catalyzed ROS Production and Cytotoxicity of aβ by Metal Ion Stripping and Redox Silencing

Bioinorganic Chemistry and Applications
Alzheimer’s disease (AD) is the most common neurodegenerative disorder associated with cognitive decline and loss of memory. It is postulated that the generation of reactive oxygen species (ROS) in Fenton-like reaction connected with Cu(II)/Cu(I) redox ...
Marianna Flora Tomasello, Maria Carmela Di Rosa, Irina Naletova, Michele Francesco Maria Sciacca, Alessandro Giuffrida, Giuseppe Maccarrone, Francesco Attanasio   +6 more
doaj   +1 more source

X-ray-Induced Heating in the Vicinity of the X-ray Interaction Point

Applied Sciences, 2023
When X-rays pass through a material, radiation damage occurs, and heat is generated at the X-ray interaction point, which can then be transferred around the X-ray irradiation site. This X-ray-induced heat transfer can affect the temperature of the sample
Jangwoo Kim, Ki Hyun Nam
doaj   +1 more source

Crystallography on a chip [PDF]

Acta Crystallographica Section D Biological Crystallography, 2012
A new chip-based crystal-mounting approach for rapid room-temperature data collection from numerous crystals is described. This work was motivated by the recent development of X-ray free-electron lasers. These novel sources deliver very intense femtosecond X-ray pulses that promise to yield high-resolution diffraction data of nanocrystals before their ...
Zarrine-Afsar, Arash, Barends, Thomas R.M., Müller, Christina, Fuchs, Martin R., Lomb, Lukas, Schlichting, Ilme, Miller, R.J. Dwayne   +6 more
openaire   +5 more sources

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The Effect of the Position of the Pyridine Nitrogen Atom in the Tridentate NN'O Schiff Base Ligand on the Type of Coordination Polymer of the Copper(II) Complex: A Crystallographic Study [PDF]

شیمی کاربردی روز
Coordination polymers (CPs) are synthesized using bridging organic ligands and metal ions, depending on the geometric coordination of the metal, the bridging ligands, and the donor atoms present in these ligands, various one-, two-, or three-dimensional ...
Kimia Forooghi, Hadi Amiri Rudbari, Reza Azadbakht   +2 more
doaj   +1 more source

An N4-Tetradentate Hydrazone Ligand That Binds in a Neutral, Mono- and Bisdeprotonated Form to Iron(II) and Zinc(II) Metal Ions

Crystals, 2021
The coordination chemistry of butane-2,3-dione bis (2′-pyridylhydrazone) towards the divalent first-row transition metals zinc and iron has been explored. Depending upon the conditions, the ligand in the six complexes was found to be either neutral, mono,
Devaraj Pandiarajan, Thomas Fox, Bernhard Spingler   +2 more
doaj   +1 more source

Nanoflow electrospinning serial femtosecond crystallography

, 2012
An electrospun liquid microjet has been developed that delivers protein microcrystal suspensions at flow rates of 0.14-3.1 µl min(-1) to perform serial femtosecond crystallography (SFX) studies with X-ray lasers.
Zouni, Athina, Gildea, Richard J, Sokaras, Dimosthenis, Yachandra, Vittal K., Sierra, Raymond G, White, William E., Hattne, Johan, Glatzel, Pieter, Milathianaki, Despina, Weng, Tsu-Chien, Schafer, Donald W, Seibert, M. Marvin, Alonso-Mori, Roberto, Bergmann, Uwe, Kern, Jan, Messinger, Johannes, Sierra, Raymond G., Seibert, M Marvin,, Zwart, Petrus H, Messerschmidt, Marc M, Hampton, Christina Y., Grosse-Kunstleve, Ralf W, Grosse-Kunstleve, Ralf W., Adams, Paul D., Yachandra, Vittal K, Miahnahri, Alan, Schafer, Donald W., Sauter, Nicholas K., Sellberg, Jonas,, McQueen, Trevor A., Boutet, Sébastien, Starodub, Dmitri, Tran, Rosalie, Bogan, Michael J, Gildea, Richard J., Adams, Paul D, Zwart, Petrus H., Lassalle-Kaiser, Benedikt, Messerschmidt, Marc M., Bogan, Michael J., Messinger, Johannes,, Echols, Nathaniel, Hampton, Christina Y, Williams, Garth J, Sellberg, Jonas, Seibert, M Marvin, Laksmono, Hartawan, Yano, Junko, Gloeckner, Carina, McQueen, Trevor A, Loh, N Duane, Loh, N. Duane, Weng, Tsu Chien, Fry, Alan R, Fry, Alan R., Hellmich, Julia, Williams, Garth J., White, William E, Sauter, Nicholas K, Glöckner, Carina   +59 more
core   +1 more source

Stable sample delivery in a viscous medium via a polyimide-based single-channel microfluidic chip for serial crystallography

, 2021
Serial crystallography (SX) provides room-temperature crystal structures with minimal radiation damage and facilitates the comprehension of molecular dynamics through time-resolved studies.
Nam, Ki Hyun, Cho, Yunje, Yunje Cho, Ki Hyun Nam   +3 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

CrystalWalk record at International Union of Crystallography (IUCR)'s crystallographic software database

, 2016
CrystalWalk record at International Union of Crystallography (IUCR)’s crystallographic software database Original URL available at https://www.iucr.org/resources/other-directories/software/crystalwalk Mirrors here and ...
International Union of Crystallography, International Union of Crystallography (5740481)   +1 more
core   +1 more source