Results 71 to 80 of about 662,036 (283)

Investigating the Effect of Inclination Angle and the Influence of Scan Parameters on the Appearance and Thermal and Mechanical Properties of Filigree Tension Rods of LPBF‐Manufactured NiTi Shape‐Memory Alloys

Advanced Engineering Materials, EarlyView.
This article investigates the dependence of the properties on the manufacturing orientation in the form of the inclination angle to the build plate of LPBF‐fabricated NiTi rods with a diameter of 150–220 µm. Metallographic, chemical, thermal, and mechanical characterization show behavior under identical manufacturing conditions that ranges from ...
Sandra Herzig, Michael Werner, Christian Rotsch   +2 more
wiley   +1 more source

Structural Characterization of Acidic M17 Leucine Aminopeptidases from the TriTryps and Evaluation of Their Role in Nutrient Starvation in Trypanosoma brucei

mSphere, 2017
Leucine aminopeptidase (LAP) is found in all kingdoms of life and catalyzes the metal-dependent hydrolysis of the N-terminal amino acid residue of peptide or amino acyl substrates.
Jennifer Timm, Maria Valente, Daniel García-Caballero, Keith S. Wilson, Dolores González-Pacanowska   +4 more
doaj   +1 more source

Molecular Packing Interaction in DNA Crystals

Crystals, 2020
DNA crystallography provides essential structural information to understand the biochemical and biological functions of oligonucleotides. Therefore, it is necessary to understand the factors affecting crystallization of DNA to develop a strategy for ...
Amen Shamim, Nazia Parveen, Vinod Kumar Subramani, Kyeong Kyu Kim   +3 more
doaj   +1 more source

Exploring serial crystallography for drug discovery [PDF]

Structure-based drug design is highly dependent on the availability of structures of the protein of interest in complex with lead compounds. Ideally, this information can be used to guide the chemical optimization of a compound into a pharmaceutical drug
J. Gunnarsson, G. Brändén, Brändén, G., M. Bjelcic, Phan, C., O. Uwangue, A. Dunge, C. Phan, H. Käck, Uwangue, O., Käck, H., Dunge, A., G. Wehlander, Bjelcic, M., Wehlander, G., Gunnarsson, J., Bjelcic, M. (author), Brändén, G.,, Wehlander, G. (author), Gunnarsson, J.,, Gunnarsson, J. (author), Bjelcic, M.,, Brändén, Gisela,, Wehlander, Gabrielle,, Monika, Bjelčić,, Uwangue, O.,, Brändén, G. (author), Phan, C.,, Käck, H.,, Uwangue, O. (author), Dunge, Andreas, Uwangue, Owens,, Dunge, A.,, Phan, C. (author), Dunge, A. (author), Käck, H. (author), Dunge, Andreas,, Lund University., Wehlander, G.,   +38 more
core   +1 more source

Viscous-medium-based crystal support in a sample holder for fixed-target serial femtosecond crystallography

, 2020
Serial femtosecond crystallography (SFX) enables the determination of the room-temperature crystal structure of macromolecules, as well as providing time-resolved molecular dynamics data in pump-probe experiments.
LEE, DONGHYEON, CHO, YUNJE, LEE, SANG JAE, PARK, SEHAN, CHUNG, WAN KYUN, NAM, KI HYUN, BAEK, SANGWON, LEE, JONG LAM, PARK, JAEHYUN, CHO, HYUN SOO, LEE, KEONDO   +10 more
core   +1 more source

Thermal Cycle–Microstructure–Property Relationships in Rail Steel Heat‐Affected Zone Simulated by Gleeble

Advanced Engineering Materials, EarlyView.
Microstructural evolution of premium rail steel during flash butt welding (FBW), comparing physically simulated heat‐affected zones with actual weld regions. Thermal cycles induce phase transformations and microstructural heterogeneity that influence weld quality and mechanical performance. These findings provide insights into optimizing FBW parameters
Emmanoelle Cintra da Cunha Araújo, João Marcos da Silva Nunes, Marcelly Cristiny Nunes de Carvalho, Alex Rojas, Cristie Luis Kugelmeier, Cristhian Ricardo Loayza Loayza, João Carlos Ferreira, Maria Veronica Goncalves Rodrigues, Rute Sayuri Kano, Isaac Araújo Furtado, Jacyara Dalylla da Silva Nunes, Jhonatan Peres de Sousa, Marcos Natan da Silva Lima, Eden Santos Silva, Gedeon Silva Reis, Samuel Filgueiras Rodrigues   +15 more
wiley   +1 more source

Laser‐Induced Graphene from Waste Almond Shells

Advanced Functional Materials, EarlyView.
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova, Anna Chiara Bressi, Marina Galliani, Attilio Marino, Gianni Ciofani, Eduardo Machado‐Charry, Hilda Gomez Bernal, Alessandra Francini, Luca Sebastiani, Francesco Greco   +9 more
wiley   +1 more source

Focus on Quantum Crystallography

IUCrJ
This editorial introduces the `Focus on Quantum Crystallography' collection, coinciding with the centenary of quantum mechanics and highlighting the convergence of crystallography and quantum theory.
Paulina M. Dominiak, Ángel Martín Pendás, Krzysztof Woźniak   +2 more
doaj   +1 more source

Self‐Assembled Crystalline Peptoid Nanomaterials as Metal‐Free Enzyme Mimics for Enhanced Carbon Dioxide Hydration and Precipitation

Advanced Functional Materials, EarlyView.
Inspired by metal‐free carbonic anhydrases (CAs) that achieve efficient catalysis without metal cofactors, we herein report a sequence‐defined supramolecular peptoid platform that mimics metal‐free CAs and exhibits hydrolytic activity via a supramolecular assembly‐mediated proton‐transfer mechanism.
Progyateg Chakma, Ying Chen, Thi Kim Hoang Trinh, Anthony R. Perez, Jonathan Gil, Maria Casco Hidalgo, Botao Hao, Kyle Whitaker, Chun‐Long Chen   +8 more
wiley   +1 more source

GPCR Conformations: Implications for Rational Drug Design

Pharmaceuticals, 2010
G protein-coupled receptors (GPCRs) comprise a large class of transmembrane proteins that play critical roles in both normal physiology and pathophysiology.
Abby L. Parrill, Debra L. Bautista
doaj   +1 more source