Results 121 to 130 of about 59,273,768 (251)
Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges
Neuroprotection, EarlyView.Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi +5 more
wiley +1 more source
Pediatric Investigation, EarlyView.This study elucidates the critical pathogenic mechanisms of pediatric Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis (EBV‐HLH), where EBV infection triggers a cytokine storm leading to immune cell hyperactivation and tissue damage. Dynamic plasma biomarkers (EBV‐DNA, ferritin, and interferon‐γ) effectively predict treatment response ...
Feifei Liu +9 more
wiley +1 more source
‘CSA-Plan’: strategies to put Climate-Smart Agriculture (CSA) into practice [PDF]
, 2017 Large-scale investment is needed to create climate-smart agriculture (CSA) systems. While many government and development agencies are integrating CSA into their policies, programmes, plans and projects, there is little guidance for operational planning
Corner-Dolloff, Caitlin +3 more
core +1 more source
Sustainable Development, EarlyView.ABSTRACT Additive Manufacturing (AM) has been identified as a potential catalyst for a paradigm shift within the construction industry, due to its capacity to enhance sustainability, reduce waste, and augment design flexibility. This study presents a systematic literature review (SLR) that explores the application of Life Cycle Assessment (LCA) in ...
Antonio Mastropasqua +3 more
wiley +1 more source
RMD OpenObjectives The TREAT EARLIER trial showed in clinically suspect arthralgia (CSA) that methotrexate induced reductions in subclinical inflammation and related disease burden during the year of treatment, which was sustained thereafter.
Hanna W van Steenbergen +5 more
doaj +1 more source
Mitigating Food Insecurity and the Impacts of Climate Change With Sustainable Digital Agriculture
Sustainable Development, EarlyView.ABSTRACT With increasing climate shocks and food insecurity, innovative approaches to agriculture have become even more significant. In this review, we examine the potential of sustainable digital agriculture in addressing some of the challenges in agriculture and food systems.
Vanisha Sharma +3 more
wiley +1 more source
Climate Smart AgricultureDairy farming underpins rural livelihoods in Kenya but is increasingly vulnerable to climate variability while contributing to greenhouse gas emissions.
Francis Onyango Oduor +2 more
doaj +1 more source
steel research international, EarlyView.The article explores how high‐strength steels and press hardening revolutionize lightweight chassis design for heavy‐duty vehicles. It reveals that press hardened steels combined with shot peening can cut weight by up to 34% and reduce environmental impact by 21%–32%.
Violeta Vargas‐Parra +7 more
wiley +1 more source
Structural Concrete, EarlyView.Abstract In precast concrete structures, optimizing the design of corbels by considering the contributions of secondary reinforcement elements can significantly improve construction economy, especially when corbels are repeated multiple times. This paper proposes a strut‐and‐tie model for reinforced concrete corbels subjected to vertical and/or ...
Rejane Martins Fernandes Canha +3 more
wiley +1 more source