Results 71 to 80 of about 39,625 (377)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Scientific Goals and In-orbit Performance of the High-energy Particle Detector on Board the CSES

open access: yesAstrophysical Journal Supplement Series, 2019
The China Seismo-Electromagnetic Satellite (CSES) aims to monitor electromagnetic, particle, and plasma perturbations in the iono-magnetosphere and inner Van Allen radiation belts originated by electromagnetic sources external and internal to the ...
P. Picozza   +48 more
semanticscholar   +1 more source

Rates for Color Shifted Microlensing Events [PDF]

open access: yes, 1995
If the objects responsible for gravitational microlensing (ML) of Galactic-bulge stars are faint dwarfs, then blended light from the lens will distort the shape of the ML light curve and shift the color of the observed star during the event.
Buchalter, Ari   +2 more
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Congruency sequence effects without feature integration or contingency learning confounds.

open access: yesPLoS ONE, 2014
The congruency effect in distracter interference (e.g., Stroop) tasks is often reduced after incongruent trials, relative to congruent trials. It has been proposed that this congruency sequence effect (CSE) results from trial-by-trial adjustments of ...
James R Schmidt, Daniel H Weissman
doaj   +1 more source

Uneven ground? Intersectional gender inequalities in the commercialized cassava seed system in Tanzania

open access: yesFrontiers in Sustainable Food Systems, 2023
Cassava (Manihot esculenta Crantz) is an important crop in Africa, especially to women who rely on it as a household staple food and source of income.
Millicent L. Liani   +7 more
doaj   +1 more source

Influence of Clustering on Cascading Failures in Interdependent Systems

open access: yes, 2018
We study the influence of clustering, more specifically triangles, on cascading failures in interdependent networks or systems, in which we model the dependence between comprising systems using a dependence graph.
La, Richard J.
core   +1 more source

Psychological symptoms in obesity and related factors [PDF]

open access: yes, 2015
Introduction: This study aimed to investigate the relationship between levels of depression and anxiety symptoms and quality of life, self-esteem in obesity.
Değirmenci, T.   +4 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

MSCM: A geomagnetic model derived from Swarm, CSES, and MSS-1 satellite data and the evolution of the South Atlantic Anomaly

open access: yesEarth and Planetary Physics
Measurements from geomagnetic satellites continue to underpin advances in geomagnetic field models that describe Earth’s internally generated magnetic field. Here, we present a new field model, MSCM, that integrates vector and scalar data from the Swarm,
Yu Gao   +4 more
doaj   +1 more source

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