Results 141 to 150 of about 3,812 (175)

Recombinant pseudorabies virus expressing E2 of classical swine fever virus (CSFV) protects against both virulent pseudorabies virus and CSFV

Antiviral Research, 2020
Both classical swine fever (CSF) and pseudorabies are highly contagious, economically significant diseases of swine in China. Although vaccination with the C-strain against classical swine fever virus (CSFV) is widely carried out and severe outbreaks of CSF seldom occur in China, CSF is sporadic in many pig herds and novel sub-subgenotypes of CSFV ...
Wu, Tong, Hao, Zheng, Guo-Xin, Li, Fei, Gao, Tong-Ling, Shan, Yan-Jun, Zhou, Hai, Yu, Yi-Feng, Jiang, Ling-Xue, Yu, Li-Wei, Li, Ning, Kong, Guang-Zhi, Tong, Ji-Chang, Li   +12 more
openaire   +2 more sources

Marker vaccine strategies and candidate CSFV marker vaccines

Vaccine, 2007
Classical swine fever (CSF) is an economically important highly contagious disease of swine worldwide. Classical swine fever virus (CSFV) is its etiological agent, and the only natural hosts are domestic pigs and wild boars. Although field CSFV strains vary in the virulence, they all result in serious losses in pig industry.
Xiao-Nan, Dong, Ying-Hua, Chen
openaire   +2 more sources

MAVS induces a host cell defense to inhibit CSFV infection

Archives of Virology, 2018
Classical swine fever virus (CSFV) infection results in highly significant economic losses. Previous studies have suggested that CSFV can be recognized by RIG-I-like receptors (RLRs) to trigger innate defenses. However, the role of mitochondrial antiviral signaling protein (MAVS), the adaptor of RLRs, is still unknown during CSFV infection.
Wang, Dong, Huifang, Lv, Cheng, Li, Yaru, Liu, Chengbao, Wang, Jihui, Lin, Yifan, Wang, Gui, Qian, Kangkang, Guo, Yanming, Zhang   +9 more
openaire   +2 more sources

Immune duration of a recombinant PRRSV vaccine expressing E2 of CSFV

Vaccine, 2020
Classical swine fever virus (CSFV) and Porcine reproductive and respiratory syndrome virus (PRRSV) are both important pathogens which seriously harm the economic swine industry worldwide. We have previously demonstrated that rPRRSV-E2 is a promising live, virus-vectored vaccine that provides 100% protection against highly pathogenic PRRSV (HP-PRRSV ...
Fei, Gao, Yifeng, Jiang, Guoxin, Li, Yujiao, Zhang, Kuan, Zhao, Haojie, Zhu, Liwei, Li, Lingxue, Yu, Hao, Zheng, Yanjun, Zhou, Wu, Tong, Guangzhi, Tong   +11 more
openaire   +2 more sources

Isolation and characterization of cytopathogenic classical swine fever virus (CSFV)

Archives of Virology, 1998
Two new classical swine fever virus (CSFV) isolates obtained from naturally infected swine were found to exhibit a cytopathogenic (cp) phenotype. According to their reactivity with monoclonal antibodies (mabs) the isolates cpBW1 and cpMVP1 were classified as antigenic types "Lothringen'92" and "Flandern'90", respectively.
A, Kosmidou, M, Büttner, G, Meyers
openaire   +2 more sources

The classic swine fever virus (CSFV) core protein can enhance de novo-initiated RNA synthesis by the CSFV polymerase NS5B

Virus Genes, 2014
Study of the classical swine fever virus (CSFV) replication is challenging because it is a BSL-3-Ag pathogen that requires specialized facilities. We developed a cell-based assay in human embryonic kidney 293T cells that can quantify the activities of NS5B, the CSFV RNA-dependent RNA polymerase.
Weiwei, Li, Yanming, Zhang, C Cheng, Kao
openaire   +2 more sources

Characterization of classical swine fever virus (CSFV) nonstructural protein 3 (NS3) helicase activity and its modulation by CSFV RNA-dependent RNA polymerase

Virus Research, 2009
Classical swine fever virus (CSFV) nonstructural protein 3 (NS3) is believed to possess three enzyme activities that are likely to be essential for virus replication: a serine protease located in the N-terminus and NTPase as well as helicase activities located in the C-terminus. In this report, we expressed NS3 helicase domain (NS3h) in E.
Guoyuan, Wen, Jinnuo, Xue, Yanping, Shen, Chuyu, Zhang, Zishu, Pan   +4 more
openaire   +2 more sources

A strategy for detecting CSFV using DNAzyme-HCR cascade amplification

Analytical Methods
The Hybridization Chain Reaction (HCR) is an isothermal amplification technique widely used for sensing nucleic acids and small molecules.
Xiuen Cao, Jiajing Cai, Zhilin He, Haofei Ji, Ruowei Sun, Xun Zhang, Chuanpin Chen, Qubo Zhu   +7 more
openaire   +2 more sources

The CSFV DNAChip: A novel diagnostic assay for classical swine fever virus

Journal of Virological Methods, 2014
A novel assay, the CSFV DNAChip, was developed to clearly and rapidly discriminate three genotypes of classical swine fever virus (CSFV). Total RNA was extracted from clinical samples and then subjected to a one-step reverse-transcription polymerase chain reaction (RT-PCR) using Cy3-labeled primers from the 5' non-coding region (NCR) of CSFV. Amplicons
Yong Kwan, Kim, Seong-In, Lim, Yoon-Young, Cho, Jae-Young, Song, JoonBae, Kim, Dong-Jun, An   +5 more
openaire   +2 more sources

Immunomodulatory effect of swine CCL20 chemokine in DNA vaccination against CSFV

Veterinary Immunology and Immunopathology, 2011
The objective of this work was to explore whether a plasmid expressing CCL20 chemokine could improve the immune response against CSFV in co-administration with a DNA vaccine expressing the E2 protein. The immunization of pigs with the DNA vaccine formulation, that contains swine CCL20 chemokine, resulted in the homogenous induction of detectable levels
Tarradas, J., Álvarez, Belén, Fraile, Luis M., Rosell, R., Muñoz Muñoz, María, Galindo-Cardiel, I., Domingo, Mariano, Domínguez, Javier, Ezquerra Martínez, Ángel, Sobrino Castelló, Francisco, Ganges, L.   +10 more
openaire   +3 more sources