Results 231 to 240 of about 9,582 (257)

MAVS induces a host cell defense to inhibit CSFV infection

Archives of Virology, 2018
Classical swine fever virus (CSFV) infection results in highly significant economic losses. Previous studies have suggested that CSFV can be recognized by RIG-I-like receptors (RLRs) to trigger innate defenses. However, the role of mitochondrial antiviral signaling protein (MAVS), the adaptor of RLRs, is still unknown during CSFV infection.
W. Dong, Huifang Lv, Cheng Li, Yaru Liu, Chengbao Wang, Jihui Lin, Yifan Wang, Gui Qian, K. Guo, Yanming Zhang   +9 more
semanticscholar   +3 more sources

Marker vaccine strategies and candidate CSFV marker vaccines

Vaccine, 2007
Classical swine fever (CSF) is an economically important highly contagious disease of swine worldwide. Classical swine fever virus (CSFV) is its etiological agent, and the only natural hosts are domestic pigs and wild boars. Although field CSFV strains vary in the virulence, they all result in serious losses in pig industry.
Xiao-Nan, Dong, Ying-Hua, Chen
openaire   +2 more sources

Circular mRNA-LNP vaccine encoding self-assembled E2-TMD-mi3 nanoparticles licit enhanced CSFV-specific immunity over commercial subunit vaccine

Frontiers in Immunology
The E2 subunit vaccine is crucial for eliminating Classical Swine Fever Virus (CSFV) due to its favorable biosafety and Differentiating Infected from Vaccinated Animals (DIVA) capability.
Chunxi Liu, Weifeng Zhai, Wenhao Nie, Conghao Zhong, Feifei Diao, Bo Yin   +5 more
semanticscholar   +1 more source

A capacitive surface stress biosensor for CSFV detection

Microelectronic Engineering, 2016
Capacitive biosensors are increasingly popular in biomedical analyses. In order to satisfy the requirements in medical diagnostics, such as high sensitivity and quick response, this paper presents a developed capacitive biosensor based on the surface stress to detect classical swine fever virus (CSFV) antigens.
Jianyan Tian, Yang Bai, Xiaoliang Tang, Shengbo Sang, Fang Wang   +4 more
openaire   +1 more source

The classic swine fever virus (CSFV) core protein can enhance de novo-initiated RNA synthesis by the CSFV polymerase NS5B

Virus Genes, 2014
Study of the classical swine fever virus (CSFV) replication is challenging because it is a BSL-3-Ag pathogen that requires specialized facilities. We developed a cell-based assay in human embryonic kidney 293T cells that can quantify the activities of NS5B, the CSFV RNA-dependent RNA polymerase.
Weiwei, Li, Yanming, Zhang, C Cheng, Kao
openaire   +2 more sources

Development of a triplex crystal digital RT-PCR for the detection of PHEV, PRV, and CSFV

Frontiers in Veterinary Science
Porcine hemagglutinating encephalomyelitis virus (PHEV), porcine pseudorabies virus (PRV), and classical swine fever virus (CSFV) are currently prevalent worldwide and cause similar neurological symptoms in infected pigs.
Kaichuang Shi, Xin Hu, Yanwen Yin, Yuwen Shi, Yi Pan, Feng Long, Shuping Feng, Zongqiang Li   +7 more
semanticscholar   +1 more source

Characterization of classical swine fever virus (CSFV) nonstructural protein 3 (NS3) helicase activity and its modulation by CSFV RNA-dependent RNA polymerase

Virus Research, 2009
Classical swine fever virus (CSFV) nonstructural protein 3 (NS3) is believed to possess three enzyme activities that are likely to be essential for virus replication: a serine protease located in the N-terminus and NTPase as well as helicase activities located in the C-terminus. In this report, we expressed NS3 helicase domain (NS3h) in E.
Guoyuan, Wen, Jinnuo, Xue, Yanping, Shen, Chuyu, Zhang, Zishu, Pan   +4 more
openaire   +2 more sources

Chimeric (marker) C-strain viruses induce clinical protection against virulent classical swine fever virus (CSFV) and reduce transmission of CSFV between vaccinated pigs

Vaccine, 2001
Two live recombinant vaccines (Flc9 and Flc11) against classical swine fever (CSF) were evaluated for their capacity to reduce transmission of virulent CSF virus (CSFV) among vaccinated pigs. In Flc9 the 5' terminal half of the E2 gene of the C-strain, a CSFV vaccine strain, was exchanged with the homologous gene of the bovine viral diarrhoea virus ...
de Smit, A.J., Bouma, A., van Gennip, H.G., de Kluijver, E.P., Moormann, R.J.   +4 more
openaire   +2 more sources

Isolation and characterization of cytopathogenic classical swine fever virus (CSFV)

Archives of Virology, 1998
Two new classical swine fever virus (CSFV) isolates obtained from naturally infected swine were found to exhibit a cytopathogenic (cp) phenotype. According to their reactivity with monoclonal antibodies (mabs) the isolates cpBW1 and cpMVP1 were classified as antigenic types "Lothringen'92" and "Flandern'90", respectively.
A, Kosmidou, M, Büttner, G, Meyers
openaire   +2 more sources

On-Site Determination of Classical Swine Fever Virus (CSFV) by a Fluorescent Microsphere-Based Lateral Flow Immunoassay Strip (FM-LFIAs) Based on Monoclonal Antibodies

Analytical Letters, 2020
Classical swine fever (CSF) is a highly infectious and lethal multisystem disease caused by the classical swine fever virus (CSFV). This virus has resulted in huge economic losses in the porcine industry.
Kaixin Xie, Hui Chen, Bin Peng, Zhiyuan Jin, Wei Xiao, Zhigang Zhang, Boyan Huang, Qifang Song, Yong Tang   +8 more
semanticscholar   +1 more source