Results 1 to 10 of about 735 (159)

Effects of dietary Chaihu-Shugan-San on egg production performance, egg quality, and hepatic lipid metabolism of late-laying hens [PDF]

Frontiers in Veterinary Science
This study aimed to evaluate the effects of Chaihu-Shugan-San (CSS) on egg production, egg quality, ovarian development, serum lipid levels, liver function, and hepatic lipid metabolism in laying hens. A total of 480 67-week-old laying hens (Jinghong No.
Zhenzhen Ji, Lei Xi, Lingli Chen, Xinlei Wang, Jieru Qin, Ailian Geng   +5 more
doaj   +2 more sources

A novel mutation in SMARCB1 associated with adult Coffin-Siris syndrome and meningioma [PDF]

Acta Biochimica et Biophysica Sinica
SMARCB1 encodes a core subunit of the SWI/SNF chromatin remodeling complex, which plays a crucial role in the regulation of gene expression.
Guo Zhenglong, Bai Jie, Liu Yang, Zhang Xianwei, Yang Wenke, Wang Jinming, Zhang Yuwei, Xiao Hai, Hao Bingtao, Liao Shixiu   +9 more
doaj   +2 more sources

Non-Isolated Dandy-Walker Malformation: Exome Sequencing Efficacy and Phenotypic Expansions. [PDF]

Clin Genet
Exome sequencing identified a diagnosis in 35% of 91 individuals with non‐isolated Dandy Walker malformation (DWM+). Only 24%–55% of these diagnoses could be made using a gene panel. We then demonstrated that DWM is a feature of disorders associated with ANKRD11, C2CD3, COL4A1, KMT2D, KRAS, OPHN1, SHOC2, SMARCB1, and WDR73.
Araji S, Zhao X, Rosenfeld JA, Lalani SR, Scott DA.   +4 more
europepmc   +2 more sources

Novel Lysosomal-Associated Transmembrane Protein 4B-Positive Stem-Like Cell Subpopulation Characterizes High-Risk Colorectal Cancer Subtypes. [PDF]

MedComm (2020)
This study identified the existence of a novel population of LAPTM4B+ tumor stem‐like cells in addition to the classical LGR5+ tumor stem‐like cells in colorectal cancer (CRC). The combination of LGR5+ and LAPTM4B+ stem‐like cells enable a more refined stratification of CRC, offering potential insights for targeted therapeutic strategies.
Fang Y, Fu T, Xiong Z, Zhang Q, Liu W, Yu K, Le A.   +6 more
europepmc   +2 more sources

Improving Bovine Embryo Development and Quality Using Bovine Oviductal Epithelial Cell-Derived Conditioned Medium (bOEC-CM). [PDF]

Vet Med Sci
The study investigated the effects of bOEC‐CM on bovine in vitro embryo development. CM from Day 3 enhances blastocyst rate and positively affects the ICM and TE in blastocysts and increases the expression of development‐specific genes. bOEC‐CM may serve as a superior supplement during the final five embryo culture days.
Hosseinabadi SK, Nazari H, Arabi M, Shams Esfandabadi N, Ahmadi E, Afzali A, Ghanaei H.   +6 more
europepmc   +2 more sources

Development and Validation of Pharmacology Concept Inventory for Concept-Based Learning: Leveraging Theory, Expert Insights, and Student Perspectives. [PDF]

Pharmacol Res Perspect
ABSTRACT Misconceptions in pharmacology can undermine learning and compromise both clinical and scientific reasoning, yet few validated tools exist to identify them. Consequently, we developed and validated the Pharmacology Concept Inventory (PCI), which can be used to identify misconceptions, assess learning gains, and evaluate teaching effectiveness.
Netere AK, Hughes T, Babey AM, Guilding C, Restini C, Hawes M, Kelly JP, Djouma E, Koenig J, McLaughlin JE, Olafuyi O, Fernandes LB, Mifsud J, Sills GJ, van Houwelingen AH, Tucker SJ, Liang W, Aronsson P, Khan FA, Hinton T, Hernandez M, Cormier L, Kelly-Laubscher R, Caetano Crowley FA, Santiago MJ, Cunningham M, Richardson JD, Karpa K, White PJ.   +28 more
europepmc   +2 more sources

Implementation of stimuli with millisecond timing accuracy in online experiments. [PDF]

PLoS ONE, 2020
Online experiments are growing in popularity. This study aimed to determine the timing accuracy of web technologies and investigate whether they can be used to support high temporal precision psychology experiments.
Zhengguo Gao, Biao Chen, Tianwen Sun, Haoqiang Chen, Kai Wang, Peipei Xuan, Zhen Liang, Zhen Liang   +7 more
doaj   +2 more sources

Development of an Artificial Intelligence Powered Medication Risk Score Calculator Application. [PDF]

Basic Clin Pharmacol Toxicol
ABSTRACT The publication explores the development of the Augmented Medication Risk Score (AUGMERIS) calculator, a web application supported by artificial intelligence, designed to automate the evaluation of medication therapies with the Danish Medication Risk Score (MERIS) method.
Bertalan Á, Angyal V, Domján P, Sædder EA, Király G, Erdélyi L, Gyimesi N, Dinya E.   +7 more
europepmc   +2 more sources

E-Variance: An Application to Assure Clinical Data Integrity and Improve Patient Safety and Workflows in Electronic Medical Records. [PDF]

Healthc Technol Lett
The RadOnc E‐Variance web‐based application, which is designed and developed to report data inconsistencies and variances noted during clinical operations. ABSTRACT Objective Ensuring critical data integrity practices are often missing from the confidence of decision‐making in the recorded clinical data.
Rahman S, Milman K, Lee TS.
europepmc   +2 more sources

Extreme Prototyping for a Community Health Worker Medical Application [PDF]

Healthcare Informatics Research
Objectives Noncommunicable diseases (NCDs) pose a significant burden, especially in low- and middle-income countries such as the Philippines. To tackle this issue, the Department of Health launched the Philippine Package of Essential Non-Communicable ...
Jan Noel Molon
doaj   +2 more sources