Design, synthesis and preliminary bio-evaluation of progestrone receptor targeting probes for breast cancer imaging with PET [PDF]
, 2016 乳腺癌是严重威胁女性健康的疾病，它的早期诊断能够有效的降低病人的死亡率。孕激素受体属于核受体超家族，有PRA和PRB两种亚型，在调节和控制卵巢，子宫和乳腺的功能方面有重要作用。研究表明，在雌激素受体阳性（ER+）的乳腺癌病人中，PR的表达与否不会对病人接受他莫西芬治疗的疗效产生影响。但是在雌激素受体表达阴性（ER-）的乳腺癌病人中，病人接受他莫西芬治疗的疗效依赖于PR的表达。因此，监测PR的表达对乳腺癌的早期诊断和ER-/PR+病人的治疗都是很重要的。PET的灵敏度高，空间分辨率好，安全性也较好 ...
吴晓伟
core
Multimodal molecular imaging technology (SPECT/CT) in the clinical application progress [PDF]
多模态分子成像设备的发展是影像学发展的里程碑，继SPECT和CT后，人们开始致力于SPECT/CT的研究。CT的多参数解剖成像与SPECT的分子成像结合，不仅提供SPECT的功能影像,而且提供CT的解剖显像,提高了传统定位、定性的准确性。对促进神经、心血管、肿瘤等方面的研究及临床诊断具有重要意义。本文从SPECT/CT成像的研究现状及其面临的挑战进行综述，并探讨SPECT/CT在生物医学中的优越性及发展前景。Multimodal molecular imaging development is ...
Guo, Jin-gang +5 more
core +2 more sources
The fMRI study of the hypothalamus function in the patients with pituitary adenoma before and after operation [PDF]
, 2015 目的：利用静息态功能磁共振影像记录技术，以垂体腺瘤患者手术前后的下丘脑区为研究对象，探讨下丘脑区功能变化与垂体腺瘤的相关性。 方法：连续性收集自2013年1月至2014年2月来我院神经外科就诊的剔除不符合标准后的78例垂体腺瘤患者进行本课题研究。纳入标准：①具有完整的诊疗记录，包括术前、术后MRI（含fMRI）检查，术前及术后1天、3天、7天、1个月、6个月的激素检测，术中完整手术录像、手术记录、日常病程记录及护理记录；②术后经过病理学（免疫组织化学法）检测后确定为垂体腺瘤的患者；排除标准 ...
肖勇
core
Zhongshan Daxue xuebao. Yixue kexue ban, 2018 【目的】探讨急性单侧上尿路梗阻肾周桥隔增厚与分肾功能的相关性。【方法】收集因结石所致急性 单侧上尿路梗阻病例50例，所有病例均行多排螺旋CT（MSCT）平扫及增强扫描；根据其是否存在肾周桥隔增厚， 分为有桥隔增厚组和无桥隔增厚组，各25例；测量双肾皮质平扫及增强扫描肾皮质期的CT值，采用独立样本 t 检验分析组间肾皮质 CT 增强值（CT 皮增-CT 皮平）及皮质期患侧与健侧皮质 CT 值比值（CT 患皮 /CT 健皮 ）的差 异。【结果】有桥隔增厚组与无桥隔增厚组比较，肾皮质增强值分别为 ...
张福康 +3 more
doaj
A Randomized Phase I/II Trial to Compare Weekly Usage with Triple Weekly Usage of Paclitaxel in Concurrent Radiochemotherapy for Patients with Locally Advanced Non-small Cell Lung Cancer [PDF]
, 2011 Background and objective Although the guidelines of the National Comprehensive Cancer Network of USA recommend that the standard therapy for locally advanced non-small cell lung cancer (LANSCLC) is concurrent chemoradiotherapy.
Anhui SHI +4 more
core
Ultrasonic and CT scanning analysis of coal-rock mass under the primary bedding structure [PDF]
In order to study the influence of the primary bedding structure on wave velocity and mechanical properties of coal-rock mass, multilayer and multi-directional ultrasonic and CT scanning tests were carried out in laboratory.
Chunyuan LI +6 more
core +1 more source
Zhongguo shiyan zhenduanxue, 2019 近年来,人们生活习惯与方式的转变,胃肠道间质肿瘤的发生率上升[1]。与此同时,临床开始加强对该肿瘤诊断与治疗的重视。就胃肠道间质肿瘤而言,诊断方法较多,不同诊断方法所取得的效果不尽相同。临床指出,多排螺旋CT增强扫描在肿瘤诊断中的效果较好[2,3]。多排螺旋CT增强扫描,是新颖的诊断方法,敏感性较高。为了明确多排螺旋CT增强扫描对胃肠道间质瘤的价值,本研究展开探析 ...
胡东 +5 more
doaj
Value of Low Tube Voltage Combined with Deep Learning Image Reconstruction Algorithm to Reduce Radiation Dose in Combined Thoracoabdominal Enhanced CT [PDF]
Objective: To investigate the effect of low tube voltage combined with deep learning image reconstruction (DLIR) on radiation dose reduction and maintaining image quality in combined chest and abdominal enhanced CT scans. Methods: (1) Phantom study.
Bei AN +6 more
core +1 more source
Zhongguo shiyan zhenduanxue, 2014 急性门静脉、肠系膜上静脉血栓形成是临床上少见的血管阻塞性疾病,Kumar[1]等建议肠系膜上静脉血栓形成分为小血管型及大血管型,小血管型仅有单纯肠系膜上静脉小血管血栓形成,而大血管型则累及大血管或合并门静脉或脾静脉血栓形成。此病容易误诊,死亡率较高[1-5],常规CT扫描速度慢,层厚较厚,对该病的敏感性相对较低,多层螺旋CT扫描速度快、通过平扫及增强扫描,利用其强大的后处理功能进行血管 ...
孙培祥
doaj
Structure of the Ambrosia Beetle (Coleoptera: Curculionidae) Mycangia Revealed Through Micro-Computed Tomography [PDF]
, 2018 Ambrosia beetles (Coleoptera: Curculionidae: Scolytinae and Platypodinae) rely on a symbiosis with fungi for their nutrition. Symbiotic fungi are preserved and transported in specialized storage structures called mycangia.
Gillett, Conrad P.D.T +7 more
core +1 more source