Results 41 to 50 of about 2,113,172 (249)
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
, 2023 This publicly available dataset namely PHE-SICH-CT-IDS, which is constructed 120 CT scans of patients with spontaneous intracerebral hemorrhage. PHE-SICH-CT-IDS contains 3,511 CT images of SICH occurring in the basal ganglia region, with associated ...
MIaMIA Group (11195799)
core +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Applied Situation of X-ray CT in Ohu University
, 2003 P(論文)In order to determine the diagnostic usefulness of X-ray Computed Tomography(CT) one year after it was set up in the maxillo-facial regions, we surveyed 162 cases (86 males and 76 females) diagnosed by CT at ohu University Dental Hospital. From this
7792 +23 more
core
Application of CT in Diagnosing Carcinoma of the Maxillary Sinuses : PART 1: Clinical Evaluation of CT and Frontal Tomography in Diagnosing Carcinoma of the Maxillary Sinuses [PDF]
, 1982 1982-03Computed and frontal tomograms were taken of 20 patients with carcinoma of the maxillary sinus and were evaluated in order to compare the diagnostic accuracy of both procedures.
MATSUBARA, KAZUHITO
core +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
A fully automatic CAD-CTC system based on curvature analysis for standard and low-dose CT data [PDF]
, 2008 Computed tomography colonography (CTC) is a rapidly evolving noninvasive medical investigation that is viewed by radiologists as a potential screening technique for the detection of colorectal polyps.
Chowdhury, Tarik A. +5 more
core +1 more source