Results 51 to 60 of about 2,517,757 (289)

Chest CT Diagnosis of COVID-19: Accuracy using CO-RADS and CTInvolvement Scoring

Journal of the Belgian Society of Radiology, 2021
Objectives: Both Reporting and Data System (CO-RADS) and CT-involvement scores (CTIS) have been proposed for evaluation of COVID-19 on chest CT. The purpose of this single-center, retrospective study was to evaluate both scoring systems to diagnose COVID-
Brecht Van Berkel, Jan Vandevenne, Kristof Coursier, Vincent Alberts, Jan Van Offenwert, Jan Verduyckt, Martijn Grieten, Wim Siemons, Geert Verswijvel   +8 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The role of cone beam computed tomography in creating of the minimally invasive endodontic access in multyrooted teeth

Эндодонтия Today, 2020
A method is presented that allows creating plastic patterns in the laboratory using computer tomography data, laser surface scanning of teeth, as well as a number of computer programs, the use of which in endodontic dentistry can accurately determine the

doaj  

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Core-CT Project news

Began with Sept.

core   +2 more sources

Core-CT connection a newsletter From the Core-CT Project . 2002: Apr.

, 2002
Began with Sept. 2001; ceased with Oct. 2003.; Numbering begins with No. 2 (Oct.

core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Radiomics and radiogenomics in intrahepatic cholangiocarcinoma

Исследования и практика в медицине
Purpose of the study. Analytical review and analysis of available literature on texture analysis of computed tomgraphy (CT) and magnetic resonance imaging (MRI) in noninvasive diagnosis of ICC and correlation with molecular genetic features and tumor ...
A. D. Smirnova, G. G. Karmazanovsky, E. V. Kondratyev, N.  A. Karelskaya, V. N. Galkin, A.  Yu. Popov, B. N. Gurmikov, D. V. Kalinin   +7 more
doaj   +1 more source

Cerebral Microbleeds in a Stroke Prevention Clinic

Diagnostics, 2019
The objective of this study was to assess the effectiveness of a stroke clinic in stroke prevention and progression of cerebral microbleeds (CMB). We conducted a retrospective observational study of patients who visited a stroke clinic between January ...
A-Hyun Cho, Lara Wadi, Daniel Chow, Peter Chang, David Floriolli, Krunal Shah, Annlia Paganini-Hill, Mark Fisher   +7 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source