Results 31 to 40 of about 1,077 (169)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Establishment of diagnostic reference levels in computed tomography for select procedures in Pudhuchery, India

open access: yesJournal of Medical Physics, 2014
Computed tomography (CT) scanner under operating conditions has become a major source of human exposure to diagnostic X-rays. In this context, weighed CT dose index (CTDI w ), volumetric CT dose index (CTDI v ), and dose length product (DLP) are ...
A Saravanakumar   +3 more
doaj   +1 more source

A prospective study on the use of ultralow-dose computed tomography with iterative reconstruction for the follow-up of patients liver and renal abscess.

open access: yesPLoS ONE, 2021
BackgroundRadiation dose reduction is a major concern in patients who undergo computed tomography (CT) to follow liver and renal abscess.ObjectivesThe purpose of this study is to investigate the feasibility of ultralow-dose CT with iterative ...
Nieun Seo   +6 more
doaj   +1 more source

Assessment of effective dose and radiation-induced cancer risk in CT-KUB

open access: yesJournal of Radiation Research and Applied Sciences, 2023
Background and objectives: Among the various imaging techniques employed for disorders related to the renal and urinary tract systems, computed tomography of kidneys, ureters, and bladder (CT-KUB) is considered the gold standard.
Salman Albeshan   +3 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Dose Assessment in Multidetector Computed Tomography (CT) of Polymethylmethacrylate (PMMA) Phantom Using American Association of Physicists in Medicine-Task Group Report No. 111 (AAPM-TG111)

open access: yesمجله دانشکده پزشکی اصفهان, 2017
Background: Computed tomography (CT) is one of the most used imaging modalities and is one of the main sources of population exposure. Recently, patient doses are estimated through CT dose index (CTDI) phantoms as a reference to calculate CTDI volume ...
Soheila Sharifian   +1 more
doaj  

Detection of intracranial hemorrhage using ultralow-dose brain computed tomography with deep learning reconstruction versus conventional-dose computed tomography

open access: yesBMC Medical Imaging
Background This study aimed to evaluate the diagnostic performance, image quality, and radiation dose among ultralow-dose protocol with deep learning reconstruction (DLR), ultralow-dose computed tomography (CT) with iterative reconstruction (IR), and ...
Chuluunbaatar Otgonbaatar   +8 more
doaj   +1 more source

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